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分流植入感染率的发生率:零%的比率永远是一个神话。

Incidence of infection rate for shunt implantation: the zero % rate is always a myth.

机构信息

Department of Pediatric Neurosurgery, Hôpital Femme Mère Enfant, 32 Avenue du Doyen Jean Lépine, 69677, Lyon Cedex, France.

Université Claude Bernard, Lyon 1, Villeurbanne, France.

出版信息

Childs Nerv Syst. 2024 Nov;40(11):3589-3595. doi: 10.1007/s00381-024-06569-4. Epub 2024 Sep 23.

DOI:10.1007/s00381-024-06569-4
PMID:39311928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11538133/
Abstract

INTRODUCTION

Paediatric CSF shunt infection rate remains a well-known complication that is not only responsible of potentially severe sequels for patients but also for economical expenses. In that study, we questioned if it is possible to attain the zero percent rate of infection that should be the goal of every paediatric neurosurgeon.

METHODS

We report our series of patients treated with a CSF device from January the first 2016 to December 31 2018.

RESULTS

In all 147 patients treated for hydrocephalus, the follow-up was of at least of 2 years from the implantation. Antibiotic-coated tubes were always used with a differential pressure valve system. A total of 172 surgical procedures were performed for 147 patients. In the follow-up time period, 4 patients presented a post-operative infection (2.3%). Two infections appeared early after the surgical procedure one after 24 h and the other after 6 days; the other two infections were diagnosed after 53 days and the other after 66 days. The germs responsible of the infections were a Staphylococcus capitals, an Escherichia coli, a Klebsiella pneumonia, and a Staphylococcus aureus.

CONCLUSIONS

Shunts will always be implanted especially in new-borns and for particular aetiologies of hydrocephalus. To reduce the rate of infection, the best thing to do is to adopt adapted protocols. Our low incidence of infection rate for shunts represent a long history to research preventive factors that helped us to improve our results during the time.

摘要

引言

小儿脑积水分流感染率仍然是一个众所周知的并发症,不仅对患者有潜在的严重后果,而且对经济也有影响。在这项研究中,我们探讨是否有可能达到零感染率,这应该是每个小儿神经外科医生的目标。

方法

我们报告了我们从 2016 年 1 月 1 日至 2018 年 12 月 31 日治疗的一组患者。

结果

在所有 147 例接受脑积水治疗的患者中,随访时间至少为植入后 2 年。始终使用抗生素涂层管和压差阀系统。为 147 名患者进行了总计 172 次手术。在随访期间,4 名患者出现术后感染(2.3%)。2 例感染发生在手术后 24 小时内,1 例发生在 6 天后;另 2 例感染发生在 53 天后,1 例发生在 66 天后。感染的病原体分别为金黄色葡萄球菌、大肠杆菌、肺炎克雷伯菌和金黄色葡萄球菌。

结论

分流器将始终被植入,特别是在新生儿和特定的脑积水病因中。为了降低感染率,最好采用适应的方案。我们的分流感染率低,这是我们长期研究预防因素的结果,这有助于我们在实践中提高治疗效果。

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The Hydrocephalus Clinical Research Network quality improvement initiative: the role of antibiotic-impregnated catheters and vancomycin wound irrigation.脑积水临床研究网络质量改进计划:抗生素浸渍导管及万古霉素伤口冲洗的作用
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Antibiotic-impregnated catheters for the prevention of CSF shunt infections: a systematic review and meta-analysis.用于预防脑脊液分流感染的抗生素浸渍导管:一项系统评价和荟萃分析。
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