Joint Department of Medical Imaging, University Health Network - Mount Sinai Hospital - Women's, College Hospital, University of Toronto, Toronto, Ontario, Canada.
Division of Urology, Department of Surgical Oncology, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Magn Reson Imaging Clin N Am. 2024 Nov;32(4):629-640. doi: 10.1016/j.mric.2024.04.001. Epub 2024 Jul 25.
Prostate cancer (PCa) is a prevalent malignancy in men, and the management of localized disease has evolved significantly in recent years. Focal therapy, wherein the biopsy confirmed site of tumor with margins is treated leaving the remaining gland intact, has emerged as a promising strategy for treating localized clinically significant PCa, minimizing side effects associated with radical therapies. We present the technical aspects, a summary of the most relevant evidence to date on the performance and safety of this technique, and the characteristic MR imaging findings during treatment, in the early posttreatment period and in the long term.
前列腺癌（PCa）是男性中常见的恶性肿瘤，近年来局部疾病的治疗方法有了显著的发展。局部治疗，即通过活检确认肿瘤边缘的部位进行治疗，而保留其余腺体的完整，已经成为治疗局部临床显著前列腺癌的一种有前途的策略，可以最大限度地减少与根治性治疗相关的副作用。我们介绍了该技术的技术方面，总结了迄今为止关于该技术的性能和安全性的最相关证据，以及治疗期间、治疗后早期和长期的特征性磁共振成像表现。
