Pain Unit, Department of Anesthesiology, Hospital Universitari Germans Trias i Pujol, Universitat Autónoma de Barcelona, Badalona, Spain.
Department of Anesthesiology, Pain Unit, Hospital Universitari de la Santa Creu i Sant Pau, Universitat Autónoma de Barcelona, Barcelona, Spain.
J Cardiothorac Vasc Anesth. 2024 Dec;38(12):3134-3142. doi: 10.1053/j.jvca.2024.08.039. Epub 2024 Sep 4.
To determine the incidence of chronic postsurgical pain (CPSP) in women after open thoracotomy. Secondary objectives were to compare relevant patient and procedural variables between women and men.
Observational cohort study.
Ten university-affiliated hospitals.
Ninety-six women and 137 men.
Scheduled open thoracotomy.
Pain histories, psychological measures, and perceived health status and catastrophizing scores were obtained. The diagnosis of chronic postsurgical pain was by physical examination at 4 months. Standard preoperative, intraoperative, and postoperative data were also recorded.
The chronic postsurgical pain incidence was significantly higher in women (53.1%) than in men (38.0%) (p = 0.023). At baseline, women had significantly worse scores on psychological measures (perception of mental state [p = 0.01], depression [p = 0.006], and catastrophizing [p < 0.001]). Women also reported more preoperative pain in the operative area (p = 0.011) and other areas (p = 0.030).
These findings show that the incidence of physician-diagnosed chronic postsurgical pain is higher in women than in men after surgeries involving thoracotomy. Sex and gender should be included in future clinical research on pain in surgical settings.
确定开胸手术后女性慢性术后疼痛（CPSP）的发生率。次要目的是比较女性和男性患者相关的手术变量。
观察性队列研究。
十所大学附属医院。
96 名女性和 137 名男性。
计划开胸手术。
疼痛史、心理测量、感知健康状况和灾难化评分。慢性手术后疼痛的诊断通过术后 4 个月的体格检查确定。还记录了标准的术前、术中、术后数据。
女性慢性术后疼痛发生率（53.1%）明显高于男性（38.0%）（p = 0.023）。在基线时，女性在心理测量方面的得分明显更差（对精神状态的感知[p = 0.01]、抑郁[p = 0.006]和灾难化[p < 0.001]）。女性还报告手术区域（p = 0.011）和其他区域（p = 0.030）的术前疼痛更多。
这些发现表明，开胸手术后，女性慢性术后疼痛的发生率高于男性。性别应纳入未来外科环境中疼痛的临床研究。
