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曲安奈德病灶内注射治疗IgG4相关性眼眶疾病后发生的视网膜中央动脉阻塞

Central Retinal Artery Occlusion Following Intralesional Triamcinolone Injection for IgG4-related Orbital Disease.

作者信息

Sanchez George, Srivatsan Sudarshan, Kim Hee Joon, Kersten Robert C

机构信息

Department of Oculoplastic and Facial Plastic Surgery, John A. Moran Eye Center, University of Utah Health, Salt Lake City, U.S.A.

出版信息

Ophthalmic Plast Reconstr Surg. 2025;41(1):e27-e30. doi: 10.1097/IOP.0000000000002804. Epub 2024 Sep 27.

DOI:10.1097/IOP.0000000000002804
PMID:39329293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11692784/
Abstract

The risk of blindness associated with periocular and facial injections is well documented. Previous cases describing vision loss following a recent periocular or facial injection have emphasized the importance of facial "danger zones." To date, the literature suggests that nearly half of all cases of central retinal artery occlusion in the setting of a recent periocular or facial injection involve an injection in or around the nose. Here, the authors report the second known case of central retinal artery occlusion following a triamcinolone injection to the lacrimal gland. A 30-year-old female with a diagnosis of IgG4-related disease underwent lacrimal gland debulking with an intralesional steroid injection. She noted OD vision loss immediately after surgery, with posterior segment examination demonstrating retinal whitening with a cherry-red spot and intra-arterial yellow-white plaques. This case serves as a reminder to clinicians regarding the risk of iatrogenic embolism following triamcinolone injections around the face with special attention drawn to the lacrimal gland.

摘要

与眼周和面部注射相关的失明风险已有充分记录。先前描述近期眼周或面部注射后视力丧失的病例强调了面部“危险区域”的重要性。迄今为止,文献表明,在近期眼周或面部注射情况下发生的所有视网膜中央动脉阻塞病例中,近一半涉及在鼻子或其周围进行的注射。在此,作者报告了第二例已知的泪腺注射曲安奈德后发生视网膜中央动脉阻塞的病例。一名诊断为IgG4相关疾病的30岁女性接受了泪腺减容术并进行了病灶内类固醇注射。她在手术后立即注意到右眼视力丧失,后部检查显示视网膜变白,有樱桃红斑和动脉内黄白色斑块。该病例提醒临床医生注意面部周围注射曲安奈德后发生医源性栓塞的风险,尤其要关注泪腺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/720196f8b10f/iop-41-e27-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/96a434c825c7/iop-41-e27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/a32ba167da6e/iop-41-e27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/6c4ff956ecb8/iop-41-e27-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/720196f8b10f/iop-41-e27-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/96a434c825c7/iop-41-e27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/a32ba167da6e/iop-41-e27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/6c4ff956ecb8/iop-41-e27-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/11692784/720196f8b10f/iop-41-e27-g004.jpg

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Korean J Ophthalmol. 2022 Apr;36(2):108-113. doi: 10.3341/kjo.2021.0130. Epub 2021 Nov 8.
2
Aspiration Before Tissue Filler-An Exercise in Futility and Unsafe Practice.注射填充前的抽吸——多此一举且不安全的做法。
Aesthet Surg J. 2022 Jan 1;42(1):89-101. doi: 10.1093/asj/sjab036.
3
Vision Loss Secondary to Facial and Periorbital Steroid Injection: A Systematic Review.
因面部和眶周类固醇注射导致的视力丧失:系统评价。
Ophthalmic Plast Reconstr Surg. 2021;37(6):511-521. doi: 10.1097/IOP.0000000000001910.
4
Ophthalmic and Central Retinal Artery Occlusion Following Triamcinolone Injection of the Lacrimal Gland.泪腺注射曲安奈德后发生的眼部及视网膜中央动脉阻塞
JAMA Ophthalmol. 2019 Dec 1;137(12):1460-1461. doi: 10.1001/jamaophthalmol.2019.3998.
5
The natural course of IgG4-related ophthalmic disease after debulking surgery: a single-centre retrospective study.减瘤手术后IgG4相关性眼病的自然病程:一项单中心回顾性研究。
BMJ Open Ophthalmol. 2019 Aug 9;4(1):e000295. doi: 10.1136/bmjophth-2019-000295. eCollection 2019.
6
Facial Danger Zones: Techniques to Maximize Safety during Soft-Tissue Filler Injections.面部危险区域:软组织填充剂注射过程中最大化安全性的技术。
Plast Reconstr Surg. 2017 May;139(5):1103-1108. doi: 10.1097/PRS.0000000000003309.
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Medicine (Baltimore). 2017 Mar;96(10):e6205. doi: 10.1097/MD.0000000000006205.
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