Suppr超能文献

妇科癌症患者及其亲属在遗传服务方面的差异获得:对健康公平性挑战的综述。

Differential Receipt of Genetic Services Among Patients With Gynecologic Cancer and Their Relatives: A Review of Challenges to Health Equity.

机构信息

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

出版信息

Clin Obstet Gynecol. 2024 Dec 1;67(4):666-671. doi: 10.1097/GRF.0000000000000893. Epub 2024 Sep 27.

Abstract

Up to 14% of endometrial cancers and 23% of epithelial ovarian cancers are associated with genetic predispositions. Referral for genetic testing and counseling can significantly impact a patient's oncologic outcomes. However, significant disparities in genetic referral and testing exist within medically underserved and minority populations in the United States. These disparities in care and access to care are multifactorial, often involving patient-level, health care-level, and system-level factors. In this review, we focus on disparities in genetic testing among patients with ovarian and uterine cancer, and the missed opportunities for primary cancer prevention among their relatives.

摘要

高达 14%的子宫内膜癌和 23%的上皮性卵巢癌与遗传易感性有关。遗传检测和咨询的转介可能会对患者的肿瘤学结局产生重大影响。然而,在美国,医疗服务不足和少数民族人群中的遗传转介和检测存在显著差异。这些在护理和获得护理方面的差异是多方面的,通常涉及患者层面、医疗保健层面和系统层面的因素。在这篇综述中,我们重点讨论了卵巢癌和子宫癌患者在基因检测方面的差异,以及他们的亲属中错过的主要癌症预防机会。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验