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[儿童术中低血压——测量与治疗]

[Intraoperative hypotension in children-Measurement and treatment].

作者信息

Bratke Sebastian, Schmid Sebastian, Sabharwal Vijyant, Jungwirth Bettina, Becke-Jakob Karin

机构信息

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Deutschland.

Anästhesie und Intensivmedizin, Cnopfsche Kinderklinik - Klinik Hallerwiese, Diakoneo, Nürnberg, Deutschland.

出版信息

Anaesthesiologie. 2024 Nov;73(11):724-734. doi: 10.1007/s00101-024-01461-x. Epub 2024 Sep 27.

DOI:10.1007/s00101-024-01461-x
PMID:39331070
Abstract

Intraoperative hypotension is a common perioperative complication in pediatric anesthesia. Oscillometric blood pressure measurement is therefore an essential part of standard perioperative monitoring in pediatric anesthesia. The optimum measurement site is the upper arm. Attention must be paid to the correct cuff size. Blood pressure should be measured before induction. In children undergoing major surgery or in critically ill children, invasive blood pressure measurement is still the gold standard. Continuous noninvasive measurement methods could be an alternative in the future.Threshold values to define hypotension remain unknown, even in awake children. There are also little data on hypotension thresholds in the perioperative setting. The most reliable measurement parameter for estimating hypotension is the mean arterial pressure. The threshold values for intraoperative hypotension are 40 mm Hg in newborns, 45 mm Hg in infants, 50 mm Hg in young children and 65 mm Hg in adolescents. Treatment should be initiated at a deviation of 10% and intensified at a deviation of 20%.Bolus administration of isotonic balanced crystalloid solutions, vasopressors and/or catecholamines are used as treatment options. Consistent and rapid intervention in the event of hypotension appears to be crucial. So far there is no evidence as to whether this leads to an improvement in outcome parameters.

摘要

术中低血压是小儿麻醉常见的围手术期并发症。因此,示波法血压测量是小儿麻醉标准围手术期监测的重要组成部分。最佳测量部位是上臂。必须注意袖带尺寸正确。诱导前应测量血压。对于接受大手术的儿童或危重症儿童,有创血压测量仍是金标准。连续无创测量方法未来可能成为一种替代方法。即使在清醒儿童中,定义低血压的阈值也尚不清楚。围手术期低血压阈值的数据也很少。估计低血压最可靠的测量参数是平均动脉压。术中低血压的阈值在新生儿中为40 mmHg,婴儿中为45 mmHg,幼儿中为50 mmHg,青少年中为65 mmHg。应在偏差10%时开始治疗,在偏差20%时加强治疗。等渗平衡晶体溶液、血管加压药和/或儿茶酚胺的推注给药用作治疗选择。低血压发生时持续快速干预似乎至关重要。到目前为止,尚无证据表明这是否会导致结局参数改善。

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本文引用的文献

1
Comparison of radial, dorsalis pedis, and posterior tibial arteries for ultrasound-guided arterial catheterisation with dynamic needle tip positioning in paediatric patients: a randomised controlled trial.超声引导下使用动态针尖定位技术经皮桡动脉、足背动脉和胫后动脉置管在儿科患者中的比较:一项随机对照试验。
Br J Anaesth. 2023 Oct;131(4):739-744. doi: 10.1016/j.bja.2023.07.022. Epub 2023 Aug 19.
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Predicting intraoperative hypotension: from hope to hype and back to reality.预测术中低血压:从希望到炒作再回归现实。
Br J Anaesth. 2023 Aug;131(2):199-201. doi: 10.1016/j.bja.2023.02.029. Epub 2023 Mar 29.
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Intraoperative monitoring of cerebrovascular autoregulation in infants and toddlers receiving major elective surgery to determine the individually optimal blood pressure - a pilot study.
对接受重大择期手术的婴幼儿进行术中脑血管自动调节监测以确定个体最佳血压——一项试点研究。
Front Pediatr. 2023 Feb 14;11:1110453. doi: 10.3389/fped.2023.1110453. eCollection 2023.
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Age-dependent changes in arterial blood pressure in neonates during the first week of life: reference values and development of a model.新生儿出生后第一周动脉血压的年龄依赖性变化:参考值及模型建立
Br J Anaesth. 2023 May;130(5):585-594. doi: 10.1016/j.bja.2023.01.024. Epub 2023 Feb 28.
5
Effective dose of ephedrine for treatment of hypotension after induction of general anaesthesia in neonates and infants less than 6 months of age: a multicentre randomised, controlled, open label, dose escalation trial.麻黄碱用于治疗6个月以下新生儿和婴儿全身麻醉诱导后低血压的有效剂量:一项多中心随机、对照、开放标签、剂量递增试验。
Br J Anaesth. 2023 May;130(5):603-610. doi: 10.1016/j.bja.2022.12.006. Epub 2023 Jan 12.
6
Capillary refill time in sepsis: A useful and easily accessible tool for evaluating perfusion in children.脓毒症中的毛细血管再充盈时间:评估儿童灌注情况的一种实用且易于获取的工具。
Front Pediatr. 2022 Nov 17;10:1035567. doi: 10.3389/fped.2022.1035567. eCollection 2022.
7
Intraoperative Blood Pressure and Long-Term Neurodevelopmental Function in Children Undergoing Ambulatory Surgery.择期手术患儿术中血压与长期神经发育功能。
Anesth Analg. 2022 Oct 1;135(4):787-797. doi: 10.1213/ANE.0000000000005853. Epub 2022 Sep 15.
8
Performance of the Hypotension Prediction Index May Be Overestimated Due to Selection Bias.低血压预测指数的性能可能因选择偏倚而被高估。
Anesthesiology. 2022 Sep 1;137(3):283-289. doi: 10.1097/ALN.0000000000004320.
9
[Hemodynamic monitoring in pediatric anesthesia].[小儿麻醉中的血流动力学监测]
Anaesthesiologie. 2022 Jun;71(6):417-425. doi: 10.1007/s00101-022-01125-8. Epub 2022 May 23.
10
Capillary refill time for the management of acute circulatory failure: a survey among pediatric and adult intensivists.毛细血管再充盈时间在急性循环衰竭管理中的应用:儿科和成人重症监护医师的调查。
BMC Emerg Med. 2022 Jul 18;22(1):131. doi: 10.1186/s12873-022-00681-x.