Köpcke Nora, Barbieri Fabian, Kasner Mario, Reinthaler Markus, Landmesser Ulf, Huemer Martin, Attanasio Philipp
Klinik für Kardiologie, Angiologie und Intensivmedizin, Deutsches Herzzentrum der Charité, Hindenburgdamm 30, 12203, Berlin, Deutschland.
Herzschrittmacherther Elektrophysiol. 2024 Dec;35(4):303-311. doi: 10.1007/s00399-024-01045-7. Epub 2024 Sep 27.
The primary therapeutic approach for severe secondary mitral regurgitation (MR) in combination with atrial fibrillation is often not clear.
OBJECTIVES/METHODS: To create a therapeutic guideline for daily clinical practice based on a case report as well as basic literature.
If a functional component is suspected, restoration of sinus rhythm may lead to a significant improvement in MR. The extent of the improvement and the time required to achieve this improvement are often difficult to predict.
The involvement of an electrophysiologist is recommended in order to assess the likelihood of successful long-term rhythm control aimed at improving MR. In unclear cases, cardioversion combined with short-term administration of antiarrhythmic medication may be useful to demonstrate potential improvement of MR in sinus rhythm.
严重继发性二尖瓣反流(MR)合并心房颤动时的主要治疗方法通常并不明确。
目的/方法:基于一份病例报告及基础文献制定一份日常临床实践治疗指南。
如果怀疑存在功能性因素,恢复窦性心律可能会使二尖瓣反流得到显著改善。改善的程度以及实现这种改善所需的时间往往难以预测。
建议由电生理学家参与评估以改善二尖瓣反流为目标的长期节律控制成功的可能性。在不明确的病例中,电复律联合短期使用抗心律失常药物可能有助于证明窦性心律时二尖瓣反流的潜在改善情况。