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左冠状动脉异常起源于对侧窦导致年轻女性晕厥性急性心肌梗死:病例报告。

Left anomalous coronary artery originating from the opposite sinus causes acute myocardial infarction with syncope in a young woman: A case report.

机构信息

Department of Cardiology, Jilin University Bethune Third Clinical Hospital, Changchun, Jilin Province, P. R. China.

Department of Radiotherapy, Jilin University Bethune Third Clinical Hospital, Changchun, Jilin Province, P. R. China.

出版信息

Medicine (Baltimore). 2024 Sep 27;103(39):e39850. doi: 10.1097/MD.0000000000039850.

DOI:10.1097/MD.0000000000039850
PMID:39331859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11441878/
Abstract

RATIONALE

The left anomalous coronary artery originating from the opposite sinus represents a distinct subtype of anomalous coronary arteries originating from the opposite sinus. A comprehensive overview encompassing clinical characteristics, diagnostic approaches, and treatment modalities for this condition is presented herein.

PATIENT CONCERNS

The patient, a 17-year-old female, was admitted to the hospital due to chest pain and syncope following multiple exercises.

DIAGNOSES

After conducting an electrocardiogram, myocardial injury markers, and echocardiography, she was diagnosed with acute myocardial infarction complicated by syncope. Further examinations including coronary angiography, coronary computed tomography angiography, and cardiac magnetic resonance imaging revealed an anomalous origin of the coronary artery with the left coronary artery (LCA) arising from the right sinus and exhibited intramural course.

INTERVENTIONS

The coronary "unroofing" technique was admitted according to her characteristics. The patient achieved successful recovery after surgery with no recurrence of chest pain or syncope during 1 year of follow-up.

OUTCOMES

Anomalous origin of the LCA is a rare congenital anatomical anomaly. Surgical intervention represents the primary approach for subsequent management of symptomatic anomalous origin of the coronary artery. Importantly, individuals with anomalous origin of the LCA from the right coronary sinus are at potential risk of sudden cardiac death.

LESSONS

Therefore, enhancing diagnostic precision and actively pursuing surgical treatment in confirmed diagnoses can effectively mitigate myocardial ischemia and prevent instances of sudden cardiac death among adolescents and athletes.

摘要

背景

起源于对侧窦的左异常冠状动脉是起源于对侧窦的异常冠状动脉的一个明显亚型。本文全面概述了这种情况的临床特征、诊断方法和治疗方式。

患者情况

患者为 17 岁女性,因多次运动后胸痛和晕厥而入院。

诊断

进行心电图、心肌损伤标志物和超声心动图检查后,诊断为急性心肌梗死并发晕厥。进一步的检查包括冠状动脉造影、冠状动脉计算机断层血管造影和心脏磁共振成像,结果显示冠状动脉异常起源,左冠状动脉(LCA)发自右窦,呈壁内走行。

干预措施

根据患者的特点,采用了冠状动脉“揭盖”技术。术后患者成功康复,随访 1 年无胸痛或晕厥复发。

结果

LCA 的异常起源是一种罕见的先天性解剖异常。对于有症状的冠状动脉异常起源,手术干预是主要的后续治疗方法。重要的是,起源于右冠状动脉窦的 LCA 异常个体存在潜在的心脏性猝死风险。

教训

因此,提高诊断准确性并积极进行手术治疗,可以有效减轻青少年和运动员的心肌缺血并预防心脏性猝死。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/364890c9f4a1/medi-103-e39850-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/f123d1d835f4/medi-103-e39850-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/364890c9f4a1/medi-103-e39850-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/f123d1d835f4/medi-103-e39850-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/a0d8058287b9/medi-103-e39850-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74d1/11441878/2d410d808497/medi-103-e39850-g003.jpg
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本文引用的文献

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J Am Heart Assoc. 2022 Oct 18;11(20):e027098. doi: 10.1161/JAHA.122.027098. Epub 2022 Oct 7.
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Coronary computed tomography angiography in children.儿童冠状动脉 CT 血管造影。
Pediatr Radiol. 2022 Dec;52(13):2498-2509. doi: 10.1007/s00247-021-05209-2. Epub 2021 Nov 4.
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Surgery for Anomalous Aortic Origin of Coronary Arteries: Technical Safeguards and Pitfalls.
冠状动脉异常起源于主动脉的手术治疗:技术保障与陷阱
Front Cardiovasc Med. 2021 May 12;8:626108. doi: 10.3389/fcvm.2021.626108. eCollection 2021.
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Outcomes after anomalous aortic origin of a coronary artery repair: A Congenital Heart Surgeons' Society Study.冠状动脉异常起源的修复术后结果:先天性心脏外科医生学会的研究。
J Thorac Cardiovasc Surg. 2020 Sep;160(3):757-771.e5. doi: 10.1016/j.jtcvs.2020.01.114. Epub 2020 Apr 13.
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Recommendations for Multimodality Assessment of Congenital Coronary Anomalies: A Guide from the American Society of Echocardiography: Developed in Collaboration with the Society for Cardiovascular Angiography and Interventions, Japanese Society of Echocardiography, and Society for Cardiovascular Magnetic Resonance.先天性冠状动脉异常多模态评估建议:美国超声心动图学会指南:与心血管造影和介入学会、日本超声心动图学会以及心血管磁共振学会合作制定。
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J Cardiovasc Med (Hagerstown). 2020 Mar;21(3):274-275. doi: 10.2459/JCM.0000000000000897.
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