衰老大脑的磁共振成像：散在性白质病变与痴呆
MR imaging of the aging brain: patchy white-matter lesions and dementia.
作者信息
Brant-Zawadzki M, Fein G, Van Dyke C, Kiernan R, Davenport L, de Groot J
出版信息
AJNR Am J Neuroradiol. 1985 Sep-Oct;6(5):675-82.
Abstract
Magnetic resonance (MR) imaging studies of the brain in five elderly patients with non-Alzheimer dementia were compared with those in two groups of nondemented control subjects. Group 1 included five subjects aged 59-66; group 2 included nine subjects aged 74-81. In all of the demented patients and in three of the subjects in the older control group, MR showed diffuse, patchy white-matter lesions. A rating scale was used to grade the severity of the changes. The results suggest a higher incidence of white-matter lesions in elderly patients with non-Alzheimer dementia and in cognitively normal elderly with advancing age.
摘要
对五名患有非阿尔茨海默病痴呆症的老年患者的脑部进行了磁共振成像（MR）研究，并与两组非痴呆对照受试者的研究结果进行了比较。第一组包括五名年龄在59 - 66岁之间的受试者；第二组包括九名年龄在74 - 81岁之间的受试者。在所有痴呆患者以及老年对照组的三名受试者中，磁共振成像显示出弥漫性、斑片状的白质病变。使用评分量表对变化的严重程度进行分级。结果表明，患有非阿尔茨海默病痴呆症的老年患者以及认知正常但年龄增长的老年人中，白质病变的发生率更高。
相似文献
1
MR imaging of the aging brain: patchy white-matter lesions and dementia.衰老大脑的磁共振成像：散在性白质病变与痴呆
AJNR Am J Neuroradiol. 1985 Sep-Oct;6(5):675-82.
2
Cognition and white matter changes on magnetic resonance imaging in dementia.痴呆症患者磁共振成像中的认知与白质变化
Arch Neurol. 1990 Apr;47(4):387-91. doi: 10.1001/archneur.1990.00530040029015.
3
MR signal abnormalities in memory disorder and dementia.记忆障碍和痴呆中的磁共振信号异常。
AJR Am J Roentgenol. 1990 Jun;154(6):1285-92. doi: 10.2214/ajr.154.6.2110743.
4
Magnetic resonance imaging in vascular dementia.
Neurology. 1987 Jan;37(1):29-36. doi: 10.1212/wnl.37.1.29.
5
White matter lesions and soluble interleukin-1 receptor type II in CSF from demented and non-demented subjects.痴呆和非痴呆受试者脑脊液中的白质病变与可溶性白细胞介素-1 II型受体
Neurochem Int. 2002 Oct;41(4):217-22. doi: 10.1016/s0197-0186(02)00025-6.
6
White matter lesions are prevalent but differentially related with cognition in aging and early Alzheimer disease.白质病变普遍存在，但在衰老和早期阿尔茨海默病中与认知的关系存在差异。
Arch Neurol. 2005 Dec;62(12):1870-6. doi: 10.1001/archneur.62.12.1870.
7
Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.老年抑郁症神经认知结局研究中的纵向磁共振成像血管变化、载脂蛋白E基因型与痴呆症的发生
Am J Geriatr Psychiatry. 2007 Oct;15(10):839-49. doi: 10.1097/JGP.0b013e318048a1a0. Epub 2007 Jul 10.
8
[Neurologic changes in the white matter of the brain in dementia].[痴呆症患者大脑白质的神经学变化]
Psychiatr Pol. 1990 Mar-Apr;24(2):100-10.
9
Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study.老年人脑白质病变的患病率：一项基于人群的磁共振成像研究。鹿特丹扫描研究。
J Neurol Neurosurg Psychiatry. 2001 Jan;70(1):9-14. doi: 10.1136/jnnp.70.1.9.
10
Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study.磁共振成像显示的脑室扩大和脑白质病变的认知相关性。鹿特丹研究。
Stroke. 1994 Jun;25(6):1109-15. doi: 10.1161/01.str.25.6.1109.
引用本文的文献
1
Structural and functional brain markers of cognitive impairment in healthcare workers following mild SARS-CoV-2 infection during the original stream.在最初一波疫情期间，轻度感染SARS-CoV-2的医护人员认知障碍的脑结构和功能标志物。
Brain Commun. 2024 Sep 30;6(5):fcae340. doi: 10.1093/braincomms/fcae340. eCollection 2024.
2
Impact of white matter hyperintensities on structural connectivity and cognition in cognitively intact ADNI participants.认知正常 ADNI 参与者的脑白质高信号对结构连接和认知的影响。
Neurobiol Aging. 2024 Mar;135:79-90. doi: 10.1016/j.neurobiolaging.2023.10.012. Epub 2023 Dec 12.
3
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.血管性痴呆和阿尔茨海默病中小血管疾病的病理生理学和可能病因。
Mol Neurodegener. 2023 Jul 11;18(1):46. doi: 10.1186/s13024-023-00640-5.
4
Silent cerebral infarction during immune TTP remission: prevalence, predictors, and impact on cognition.免疫性 TTP 缓解期的静默性脑梗死：患病率、预测因素及其对认知的影响。
Blood. 2023 Jul 27;142(4):325-335. doi: 10.1182/blood.2023019663.
5
Gait and falls in cerebral small vessel disease: a systematic review and meta-analysis.脑小血管病的步态和跌倒：系统评价和荟萃分析。
Age Ageing. 2023 Mar 1;52(3). doi: 10.1093/ageing/afad011.
6
Predicted disconnectome associated with progressive periventricular white matter ischemia.与进行性脑室周围白质缺血相关的预测性脑连接组
Cereb Circ Cogn Behav. 2021 Jul 1;2:100022. doi: 10.1016/j.cccb.2021.100022. eCollection 2021.
7
Night-Time Non-dipping Blood Pressure and Heart Rate: An Association With the Risk of Silent Small Vessel Disease in Patients Presenting With Acute Ischemic Stroke.夜间血压和心率非勺型变化：与急性缺血性卒中患者隐匿性小血管疾病风险的关联
Front Neurol. 2021 Nov 16;12:719311. doi: 10.3389/fneur.2021.719311. eCollection 2021.
8
Influence of Striatal Dopamine, Cerebral Small Vessel Disease, and Other Risk Factors on Age-Related Parkinsonian Motor Signs.纹状体多巴胺、脑小血管病及其他危险因素对与年龄相关的帕金森运动征象的影响。
J Gerontol A Biol Sci Med Sci. 2020 Mar 9;75(4):696-701. doi: 10.1093/gerona/glz161.
9
Cross-sectional and longitudinal associations between total and regional white matter hyperintensity volume and cognitive and motor function in Parkinson's disease.横断面和纵向研究帕金森病患者全脑和局部脑白质高信号体积与认知和运动功能的相关性。
Neuroimage Clin. 2019;23:101870. doi: 10.1016/j.nicl.2019.101870. Epub 2019 May 23.
10
Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions.亚临床脑白质病变患者的下尿路症状
J Aging Res. 2018 Jul 30;2018:1582092. doi: 10.1155/2018/1582092. eCollection 2018.
Zotero 插件