衰老大脑的磁共振成像：散在性白质病变与痴呆
MR imaging of the aging brain: patchy white-matter lesions and dementia.
作者信息
Brant-Zawadzki M, Fein G, Van Dyke C, Kiernan R, Davenport L, de Groot J
出版信息
AJNR Am J Neuroradiol. 1985 Sep-Oct;6(5):675-82.
Abstract
Magnetic resonance (MR) imaging studies of the brain in five elderly patients with non-Alzheimer dementia were compared with those in two groups of nondemented control subjects. Group 1 included five subjects aged 59-66; group 2 included nine subjects aged 74-81. In all of the demented patients and in three of the subjects in the older control group, MR showed diffuse, patchy white-matter lesions. A rating scale was used to grade the severity of the changes. The results suggest a higher incidence of white-matter lesions in elderly patients with non-Alzheimer dementia and in cognitively normal elderly with advancing age.
摘要
对五名患有非阿尔茨海默病痴呆症的老年患者的脑部进行了磁共振成像（MR）研究，并与两组非痴呆对照受试者的研究结果进行了比较。第一组包括五名年龄在59 - 66岁之间的受试者；第二组包括九名年龄在74 - 81岁之间的受试者。在所有痴呆患者以及老年对照组的三名受试者中，磁共振成像显示出弥漫性、斑片状的白质病变。使用评分量表对变化的严重程度进行分级。结果表明，患有非阿尔茨海默病痴呆症的老年患者以及认知正常但年龄增长的老年人中，白质病变的发生率更高。
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