Haghbin M, Kramer S, Patchefsky A S, Prestipino A J, Diener-West M D
Am J Clin Oncol. 1985 Oct;8(5):384-92. doi: 10.1097/00000421-198510000-00009.
Between 1958-1983, 79 patients with a diagnosis of epithelial tumor of the nasopharynx received definitive irradiation at Thomas Jefferson University Hospital. Seventy-two percent of the patients had a Stage IV lesion. The dose to the nasopharynx was over 6,000 cGy in all but four patients. The 5- and 10-year actuarial survivals were 33% and 19% respectively. The 5-year disease-free survival was 33%. Histology had no bearing on survival. Survival was influenced by the stage of primary tumor and nodes. Advanced nodal disease correlated with distant metastasis, being present in 13/15 cases with hematogenous spread.
1958年至1983年间，79例被诊断为鼻咽上皮肿瘤的患者在托马斯·杰斐逊大学医院接受了根治性放疗。72%的患者有IV期病变。除4例患者外，所有患者鼻咽部的照射剂量均超过6000 cGy。5年和10年精算生存率分别为33%和19%。5年无病生存率为33%。组织学与生存率无关。生存率受原发肿瘤和淋巴结分期的影响。晚期淋巴结疾病与远处转移相关，15例血行转移患者中有13例出现晚期淋巴结疾病。
