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长睡眠时间与慢性肾脏病男性成年人的腹主动脉钙化有关:NHANES 2013-2014。

Long sleep duration is associated with abdominal aortic calcification among male adults with chronic kidney disease: NHANES 2013-2014.

机构信息

Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

出版信息

Sci Rep. 2024 Sep 27;14(1):22076. doi: 10.1038/s41598-024-72879-x.

Abstract

There are no studies exploring the correlation between sleep duration and abdominal aortic calcification (AAC). This study aims to investigate this relationship and its significance. Additionally, given the higher prevalence of sleep disorders and AAC in patients with chronic kidney disease (CKD), we conducted further studies in this population. We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014. Sleep duration was assessed by a sleep questionnaire and categorized into 2-5, 6-8, and ≥ 9 h. The AAC-24 score is determined using the Kauppila scoring system and used for AAC assessment. Multivariable linear and logistic regression analysis were used to explore the relationship between sleep duration and AAC. Among the 2,996 participants, 14.29% reported nightly short sleep (2-5 h), 77.64% reported intermediate sleep (6-8 h), and 8.08% reported long sleep (≥ 9 h). After adjusting for potential confounding factors, among male participants with CKD, long sleep (≥ 9 h) significantly increased AAC-24 scores compared with intermediate sleep (6-8 h) (β: 2.12; 95% CI: 0.75, 3.50), and the risk of severe AAC (SAAC) was increased by 1.55 times (OR: 2.55; 95% CI: 1.02, 6.36). And among female CKD and non-CKD participants, sleep duration was not associated with AAC. Long sleep duration increases the risk of AAC among male adults with CKD. Prospective studies are needed to confirm this finding.

摘要

目前尚无研究探讨睡眠时间与腹主动脉钙化(AAC)之间的相关性。本研究旨在探讨这种关系及其意义。此外,鉴于慢性肾脏病(CKD)患者中睡眠障碍和 AAC 的发病率较高,我们在该人群中进行了进一步的研究。我们分析了 2013-2014 年全国健康和营养调查(NHANES)的数据。通过睡眠问卷评估睡眠时间,并分为 2-5、6-8 和≥9 小时。使用 Kauppila 评分系统确定 AAC-24 评分,用于 AAC 评估。多变量线性和逻辑回归分析用于探讨睡眠时间与 AAC 之间的关系。在 2996 名参与者中,14.29%报告每晚短睡(2-5 小时),77.64%报告中等睡眠(6-8 小时),8.08%报告长睡(≥9 小时)。在调整了潜在混杂因素后,在患有 CKD 的男性参与者中,长睡(≥9 小时)与中等睡眠(6-8 小时)相比,AAC-24 评分显著增加(β:2.12;95%CI:0.75,3.50),严重 AAC(SAAC)的风险增加 1.55 倍(OR:2.55;95%CI:1.02,6.36)。而在患有 CKD 和非 CKD 的女性参与者中,睡眠时间与 AAC 无关。长睡眠时间会增加 CKD 成年男性患 AAC 的风险。需要前瞻性研究来证实这一发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6294/11436971/ff38139c5a71/41598_2024_72879_Fig1_HTML.jpg

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