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海地一家三级医院急诊科的红细胞输血:患者特征及供应挑战

Red blood cell transfusion in a tertiary Haitian hospital's emergency department: patient characteristics and availability challenges.

作者信息

Jacques Flawendjee Djaweelentz, Julmisse Samentha Cyndie, Laurore Ange Cindy, Lefruit Ralph Mackenson, Chery Maurice Junior, Dubique Kobel

机构信息

Hôpital Universitaire de Mirebalais, Mirebalais, Center, Haiti.

出版信息

Int J Emerg Med. 2024 Sep 27;17(1):128. doi: 10.1186/s12245-024-00672-8.

DOI:10.1186/s12245-024-00672-8
PMID:39333880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11438301/
Abstract

BACKGROUND

Red blood cell (RBC) transfusions are essential for many patients admitted to emergency departments (ED). However, accessibility to red cell transfusions is often limited, especially in low-income countries such as Haiti. This article aims to determine the proportion of patients requiring emergency transfusion, transfused patients' characteristics, as well as the response rate and timeliness of blood product delivery for requests made.

METHODS

A retrospective study was conducted among all patients with RBC transfusion indications from January to June 2022 at the ED of Mirebalais Teaching Hospital. The parameters studied included transfusion indications, pre-transfusion hemoglobin levels, and delay from prescription to transfusion.

RESULTS

During the study period, 3993 patients received treatment in the ED. The proportion of patients requiring RBCs was 7.69%, including 145 males and 117 females, with a median age of 43 [30-56] years. Only 21.7% of these patients received a transfusion. The average pre-transfusion hemoglobin level was 4.75 ± 1.68 g/dL. The most common transfusion's indications were infection/sepsis (36.74%), trauma (23.48%), and cancer (21.57%). The median time delay from prescription to transfusion was 2.37 [0.97-4.93] days. The study identified significant associations between RBC transfusion probability and patient factors like hemoglobin levels, patient disposition, urgency of RBC request, and length of stay.

CONCLUSION

RBC transfusion requests are frequent in the ED of Mirebalais Teaching Hospital, with a relatively high transfusion delay. Further studies on the relevance of RBC requests and ways to reduce delay from prescription to transfusion would be beneficial to improve this situation.

摘要

背景

红细胞(RBC)输血对于许多急诊科(ED)收治的患者至关重要。然而,红细胞输血的可及性往往有限,尤其是在海地等低收入国家。本文旨在确定需要紧急输血的患者比例、输血患者的特征,以及所提输血请求的血液制品交付响应率和及时性。

方法

对2022年1月至6月在米雷巴莱教学医院急诊科所有有红细胞输血指征的患者进行了一项回顾性研究。研究参数包括输血指征、输血前血红蛋白水平以及从开处方到输血的延迟时间。

结果

在研究期间,3993名患者在急诊科接受治疗。需要红细胞的患者比例为7.69%,其中男性145名,女性117名,中位年龄为43[30 - 56]岁。这些患者中只有21.7%接受了输血。输血前平均血红蛋白水平为4.75±1.68 g/dL。最常见的输血指征是感染/脓毒症(36.74%)、创伤(23.48%)和癌症(21.57%)。从开处方到输血的中位延迟时间为2.37[0.97 - 4.93]天。该研究确定了红细胞输血概率与患者因素如血红蛋白水平、患者处置情况、红细胞请求的紧迫性和住院时间之间存在显著关联。

结论

米雷巴莱教学医院急诊科红细胞输血请求频繁,输血延迟相对较高。进一步研究红细胞请求的相关性以及减少从开处方到输血延迟的方法将有助于改善这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c9/11438301/8bf1c263f086/12245_2024_672_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c9/11438301/2b4fc1a742f3/12245_2024_672_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c9/11438301/8bf1c263f086/12245_2024_672_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c9/11438301/2b4fc1a742f3/12245_2024_672_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c9/11438301/8bf1c263f086/12245_2024_672_Fig3_HTML.jpg

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本文引用的文献

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Status of hospital-based blood transfusion services in low-income and middle-income countries: a cross-sectional international survey.中低收入国家基于医院的输血服务现状:一项国际横断面调查。
BMJ Open. 2022 Feb 15;12(2):e055017. doi: 10.1136/bmjopen-2021-055017.
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Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study.急诊科的红细胞输血:一项观察性横断面多中心研究
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Transfusion, mortality and hemoglobin level: Associations among emergency department patients in Kigali, Rwanda.
输血、死亡率与血红蛋白水平:卢旺达基加利急诊科患者之间的关联
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