Belleri Paola, Mazzuca Giorgia, Pietrobelli Angelo, Zampieri Nicola, Piacentini Giorgio, Zaffanello Marco, Pecoraro Luca
Pediatric Clinic, Department of Surgical Sciences, Dentistry, Pediatrics and Gynecology, University of Verona, 37126 Verona, Italy.
Pediatric Surgical Unit, Department of Surgical Sciences, University of Verona, 37126 Verona, Italy.
Children (Basel). 2024 Aug 29;11(9):1056. doi: 10.3390/children11091056.
Down's syndrome (DS), or Trisomy 21, represents the most common chromosomal abnormality in live births, characterized by an extra chromosome 21. Children affected by Down's syndrome are more susceptible to the development of obesity and of becoming overweight compared with other children. Furthermore, they seem to present a more unfavorable lipid profile than the non-DS obese pediatric population. Diet and physical activity are closely related to the development of overweight and obesity, and they can be assessed using questionnaires such as the Mediterranean Diet Quality Index in children and adolescents (KIDMED) and the Godin-Shephard Leisure-Time Physical Activity Questionnaire. This review aims to undertake a comprehensive analysis of the intricate interplay between diet and physical activity in children affected by Down's syndrome. Specifically, it seeks to deepen understanding regarding the question of how diet and exercise can influence and prevent the development of overweight and obesity in that special pediatric population.
唐氏综合征（DS），即21三体综合征，是活产儿中最常见的染色体异常疾病，其特征是多了一条21号染色体。与其他儿童相比，患唐氏综合征的儿童更容易出现肥胖和超重。此外，与非唐氏综合征肥胖儿童群体相比，他们的血脂谱似乎更不理想。饮食和身体活动与超重和肥胖的发展密切相关，可以通过儿童和青少年地中海饮食质量指数（KIDMED）以及戈丁-谢泼德休闲时间身体活动问卷等问卷进行评估。本综述旨在全面分析唐氏综合征患儿饮食与身体活动之间的复杂相互作用。具体而言，它试图加深对饮食和运动如何影响和预防该特殊儿童群体超重和肥胖问题的理解。
