Chiellino Serena, Fortini Viola, Castellani Chiara, Vasarri Pierluigi
Paediatric and Neonatologic Unit, Santo Stefano Hospital, 59100 Prato, Italy.
Paediatric Pulmonary Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
Children (Basel). 2024 Sep 15;11(9):1126. doi: 10.3390/children11091126.
Isolated musculoskeletal infantile myofibroma is a rare tumor of pediatric age. The majority of cases are seen in children under two years old, but it can occur at any age as a painless enlarging mass that involves bone, skin, or soft tissue, typically accompanied by compression symptoms. Perineural involvement is extremely rare in myofibromas. Neurological impairment can occur during infancy but isolated nerve palsy, particularly in peripheral nerves within the upper extremity, is very uncommon. Neonatal radial nerve palsy is a rare entity caused by different conditions. Among these, we mention local tumors affecting peripheral nerves, such as myofibroma. There are few cases described in the literature, which mainly concern adult patients. The authors present a case of congenital isolated radial nerve palsy in a newborn with MF of the right elbow, which resulted in impairment of the wrist and finger extension. Following a six-month monitoring period, the patient underwent surgical treatment to restore function to his right wrist and hand. This involved excising the infiltrated radial nerve segment associated with palliative surgery. Despite the benignity of this lesion, severe nerve damage and perineural involvement may require surgical treatment with nerve resection and reconstruction.
孤立性肌肉骨骼婴儿肌纤维瘤是一种儿科罕见肿瘤。大多数病例见于两岁以下儿童，但可发生于任何年龄，表现为无痛性肿块，累及骨骼、皮肤或软组织，通常伴有压迫症状。肌纤维瘤中神经周围受累极为罕见。婴儿期可出现神经功能障碍，但孤立性神经麻痹，尤其是上肢周围神经麻痹非常少见。新生儿桡神经麻痹是一种由多种不同情况引起的罕见病症。其中，我们提到了影响周围神经的局部肿瘤，如肌纤维瘤。文献中描述的病例很少，主要涉及成年患者。作者报告了一例新生儿先天性孤立性桡神经麻痹，其右肘患有肌纤维瘤，导致手腕和手指伸展功能受损。经过六个月的监测期后，患者接受了手术治疗以恢复右手腕和手部功能。这包括切除与姑息性手术相关的浸润性桡神经节段。尽管该病变为良性，但严重的神经损伤和神经周围受累可能需要进行神经切除和重建的手术治疗。
