da Silva Thaís Nogueira, Ribeiro Vivian Finotti, Apaza Margot Carol Condori, Romana Lívia Gallerani, de Moraes Íbis Ariana Peña, Dias Eduardo Dati, Roizenblatt Suely Steinschreiber, Martinez Juliana Perez, Magalhães Fernando Henrique, Massa Marcelo, Ré Alessandro Hervaldo Nicolai, de Araújo Luciano Vieira, da Silva-Magalhães Talita Dias, de Mello Monteiro Carlos Bandeira
Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of São Paulo (FMUSP), São Paulo, Brazil.
Graduate Program in Medicine (Cardiology), Escola Paulista de Medicina, Federal University of São Paulo (EPM/UNIFESP), São Paulo, Brazil.
Brain Sci. 2024 Sep 18;14(9):928. doi: 10.3390/brainsci14090928.
BACKGROUND/OBJECTIVES: Fibromyalgia (FM) is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and impaired motor performance. This study aimed to investigate the effects of transcranial direct current stimulation (tDCS) during virtual reality (VR) tasks on the motor performance of women with FM.
Participants were divided into two groups: Group A received active tDCS for 10 days followed by sham tDCS for 10 days, while Group B received the opposite sequence. Both groups performed VR tasks using MoveHero software (v. 2.4) during the tDCS sessions. Motor performance was assessed by the number of hits (movement with correct timing to reach the targets) and absolute (accuracy measure) and variable (precision measure) errors during VR tasks. Participants were 21 women, aged 30-50 years, and diagnosed with FM.
Group A, which received active tDCS first, presented significant improvements in motor performance (number of hits and absolute and variable errors). The benefits of active tDCS persisted into the sham phase, suggesting a lasting neuroplastic effect.
tDCS during VR tasks significantly improved motor performance in women with FM, particularly in complex, extensive movements. These findings indicate that tDCS enhances neuroplasticity, leading to sustained motor improvements, making it a promising therapeutic tool in FM rehabilitation.
背景/目的：纤维肌痛（FM）是一种慢性疾病，其特征为广泛的肌肉骨骼疼痛、疲劳和运动表现受损。本研究旨在调查虚拟现实（VR）任务期间经颅直流电刺激（tDCS）对FM女性运动表现的影响。
参与者分为两组：A组先接受10天的有源tDCS，然后接受10天的伪tDCS，而B组接受相反的顺序。两组在tDCS疗程期间使用MoveHero软件（版本2.4）执行VR任务。通过VR任务期间的命中次数（以正确时间到达目标的动作）以及绝对误差（准确性测量）和可变误差（精确性测量）来评估运动表现。参与者为21名年龄在30至50岁之间、被诊断患有FM的女性。
先接受有源tDCS的A组在运动表现（命中次数以及绝对误差和可变误差）方面有显著改善。有源tDCS的益处持续到伪刺激阶段，表明存在持久的神经可塑性效应。
VR任务期间的tDCS显著改善了FM女性的运动表现，尤其是在复杂、广泛的运动中。这些发现表明tDCS增强了神经可塑性，导致运动持续改善，使其成为FM康复中一种有前景的治疗工具。
