Meloni Antonella, Cau Riccardo, Saba Luca, Positano Vincenzo, De Gori Carmelo, Occhipinti Mariaelena, Celi Simona, Bossone Eduardo, Bertacchi Jacopo, Punzo Bruna, Mantini Cesare, Cavaliere Carlo, Maffei Erica, Cademartiri Filippo
Bioengineering Unit, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.
Department of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.
Diagnostics (Basel). 2024 Sep 11;14(18):2012. doi: 10.3390/diagnostics14182012.
Photon counting computed tomography (PCCT) represents a paradigm shift from conventional CT imaging, propelled by a new generation of X-ray detectors capable of counting individual photons and measuring their energy. The first part of this narrative review is focused on the technical aspects of PCCT and describes its key advancements and benefits compared to conventional CT but also its limitations. By synthesizing the existing literature, the second part of the review seeks to elucidate the potential of PCCT as a valuable tool for assessing carotid artery disease. Thanks to the enhanced spatial resolution and image quality, PCCT allows for an accurate evaluation of carotid luminal stenosis. With its ability to finely discriminate between different tissue types, PCCT allows for detailed characterization of plaque morphology and composition, which is crucial for assessing plaque vulnerability and the risk of cerebrovascular events.
光子计数计算机断层扫描(PCCT)代表了从传统CT成像的范式转变,这一转变由能够对单个光子进行计数并测量其能量的新一代X射线探测器推动。本叙述性综述的第一部分聚焦于PCCT的技术方面,描述了与传统CT相比其关键进展和优势,也阐述了其局限性。通过综合现有文献,综述的第二部分旨在阐明PCCT作为评估颈动脉疾病的有价值工具的潜力。由于空间分辨率和图像质量的提高,PCCT能够准确评估颈动脉管腔狭窄。凭借其对不同组织类型的精细区分能力,PCCT能够对斑块形态和成分进行详细表征,这对于评估斑块易损性和脑血管事件风险至关重要。