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麻醉对老年股骨近端骨折患者术后住院期间发病率和死亡率的影响。

Anesthesia's Influence on Postoperative In-Hospital Morbidity-Mortality in Proximal Femoral Fractures in the Elderly.

机构信息

Department of Orthopedic Surgery, Wolfson Medical Center, Affiliated to the Sackler School of Medicine, Holon 5822012, Israel.

Department of Anesthesia, Wolfson Medical Center, Affiliated to the Sackler School of Medicine, Holon 5822012, Israel.

出版信息

Medicina (Kaunas). 2024 Sep 4;60(9):1446. doi: 10.3390/medicina60091446.

Abstract

The incidence of proximal femoral fractures (PFFs) is rising, causing significant morbidity and mortality. Regional anesthesia (RA)'s benefits include the avoidance of intubation and mechanical ventilation, decreased blood loss, and improved analgesia. General anesthesia (GA) offers improved hemodynamic stability. This study examines the in-hospital post-surgical morbidity and mortality seen in PFFs in a cohort of the elderly undergoing GA or RA. This is a retrospective cohort study of 319 PFF patients older than 65 years over a single year. In total, 73.7% of patients underwent GA. The patient characteristics were identical between groups, except for smoking. Hypertension was the most frequent comorbidity, followed by hyperlipidemia, NIDDM, and IHD. The overall patient complication rate was 11.4%. Pneumonia was the most common complication (5.1% in GA, 8.4% in RA). A total of 0.9% of patients required ICU admission. Overall, the in-hospital mortality rate was 2.3%, with no statistically significant difference between GA and RA. The GA and RA cohorts were similar in terms of their patient demographics, medical history, and preoperative parameters. In total, 73% of surgeries were under GA. No statistically significant differences were found in total anesthesia time or complication rates. We did not find a difference between general and spinal anesthesia regarding complication rates, anesthesia time, or morbidity. General anesthesia remains best suited for patients receiving anticoagulation treatment and undergoing semi-urgent surgery, but, other than that, the mode of anesthesia administered remains up to the anesthesiologist's preference.

摘要

股骨近端骨折(PFF)的发病率正在上升,导致发病率和死亡率显著增加。区域麻醉(RA)的益处包括避免插管和机械通气、减少失血和改善镇痛。全身麻醉(GA)提供更好的血流动力学稳定性。本研究检查了在接受 GA 或 RA 的老年 PFF 患者队列中观察到的住院术后发病率和死亡率。 这是一项回顾性队列研究,纳入了 1 年内 319 名年龄超过 65 岁的 PFF 患者。 共有 73.7%的患者接受了 GA。组间患者特征相同,除了吸烟情况。高血压是最常见的合并症,其次是高脂血症、NIDDM 和 IHD。总体患者并发症发生率为 11.4%。肺炎是最常见的并发症(GA 中为 5.1%,RA 中为 8.4%)。共有 0.9%的患者需要入住 ICU。总体而言,住院死亡率为 2.3%,GA 和 RA 之间无统计学差异。GA 和 RA 队列在患者人口统计学、病史和术前参数方面相似。共有 73%的手术在 GA 下进行。总麻醉时间或并发症发生率无统计学差异。 我们没有发现全身麻醉和椎管内麻醉在并发症发生率、麻醉时间或发病率方面存在差异。全身麻醉仍然最适合接受抗凝治疗和接受半紧急手术的患者,但除此之外,麻醉方式仍由麻醉师的偏好决定。

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