Almaadawy Omar, Uretsky Barry F, Krittanawong Chayakrit, Birnbaum Yochai
Department of Internal Medicine, MedStar Health, Baltimore, MD 21218, USA.
Division of Cardiovascular Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
J Clin Med. 2024 Sep 19;13(18):5562. doi: 10.3390/jcm13185562.
Exercise stress testing (EST) is commonly used to evaluate chest pain, with some labs using 85% of age-predicted maximum heart rate (APMHR) as an endpoint for EST. The APMHR is often calculated using the formula 220-age. However, the accuracy of this formula and 85% APMHR as an endpoint may be questioned. Moreover, failing to reach 85% APMHR (known as chronotropic insufficiency) may also indicate poor cardiovascular prognosis, but measurements, such as percentage heart rate reserve (%HRR), maximum rate pressure product (MRPP), and the maximum metabolic equivalent of tasks (METs) reached during EST may provide better prediction of cardiovascular outcomes than not reaching 85% of APMHR. There is a need to incorporate comprehensive measurements to improve the diagnostic and prognostic capabilities of EST.
运动应激试验(EST)常用于评估胸痛,一些实验室将年龄预测最大心率(APMHR)的85%作为EST的终点。APMHR通常使用公式220 - 年龄来计算。然而,该公式以及85% APMHR作为终点的准确性可能受到质疑。此外,未能达到85% APMHR(称为变时性功能不全)也可能表明心血管预后不良,但EST期间达到的心率储备百分比(%HRR)、最大心率血压乘积(MRPP)以及最大代谢当量(METs)等测量指标,可能比未达到APMHR的85%能更好地预测心血管结局。需要纳入综合测量指标以提高EST的诊断和预后能力。