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评估持续血糖监测对1型糖尿病患者勃起功能障碍的影响:聚焦于降低血糖变异性和炎症反应

Evaluating the Impact of Continuous Glucose Monitoring on Erectile Dysfunction in Type 1 Diabetes: A Focus on Reducing Glucose Variability and Inflammation.

作者信息

Tecce Nicola, Menafra Davide, Proganò Mattia, Tecce Mario Felice, Pivonello Rosario, Colao Annamaria

机构信息

Department of Clinical Medicine and Surgery, Department of Endocrinology, University Federico II of Naples, 80138 Naples, Italy.

Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.

出版信息

Healthcare (Basel). 2024 Sep 12;12(18):1823. doi: 10.3390/healthcare12181823.

Abstract

Type 1 diabetes (T1D) severely impairs metabolic control and can lead to erectile dysfunction (ED) through hyperglycemia-induced vascular damage, autonomic neuropathy, and psychological distress. This review examines the role of continuous glucose monitoring (CGM) in ameliorating ED by addressing glucose variability and inflammation. A comprehensive analysis of studies and clinical trials was conducted to evaluate the impact of CGM on metabolic control, inflammatory responses, and vascular health in patients with T1D. Evidence suggests that CGM systems significantly stabilize blood glucose levels and reduce hyper- and hypoglycemic episodes that contribute to endothelial dysfunction and ED. CGM's real-time feedback helps patients optimize metabolic control, improve vascular health, and reduce inflammation. CGM has the potential to redefine ED management in patients with T1D by improving glycemic control and reducing the physiological stressors that cause ED, potentially improving quality of life and sexual health. Further research is warranted to explore the specific benefits of CGM for ED management.

摘要

1型糖尿病(T1D)严重损害代谢控制,并可通过高血糖诱导的血管损伤、自主神经病变和心理困扰导致勃起功能障碍(ED)。本综述通过探讨血糖变异性和炎症来研究连续血糖监测(CGM)在改善ED方面的作用。对研究和临床试验进行了全面分析,以评估CGM对T1D患者代谢控制、炎症反应和血管健康的影响。证据表明,CGM系统可显著稳定血糖水平,并减少导致内皮功能障碍和ED的高血糖和低血糖发作。CGM的实时反馈有助于患者优化代谢控制、改善血管健康并减轻炎症。CGM有潜力通过改善血糖控制和减少导致ED的生理应激因素来重新定义T1D患者的ED管理,有可能改善生活质量和性健康。有必要进行进一步研究以探索CGM对ED管理的具体益处。

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