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[大鼠下橄榄核破坏后红核神经元的活动]

[Activity of neurons of the red nucleus after destruction of the inferior olive in the rat].

作者信息

Billard J M, Daniel H

出版信息

C R Acad Sci III. 1985;301(5):251-3.

PMID:3933780
Abstract

The spontaneous frequency of discharge of the red nucleus neurones has been evaluated in the rat before and after total and bilateral destruction of the inferior olive by 3-acetylpyridine. The suppression of the inferior olive increasing the cerebellar inhibition, produces, as a consequence, a consequence, a disfacilitation of the activity of the red nucleus neurones. The process persists for a few days, then a progressive compensation takes place. A month later the average frequency of discharge is recovered but a normal unit activity and motor behaviour are not restaured.

摘要

通过3-乙酰吡啶对大鼠双侧下橄榄核进行完全损毁前后,对红核神经元的自发放电频率进行了评估。下橄榄核抑制作用增强,从而增加小脑抑制,结果导致红核神经元活动的去抑制。这个过程持续几天,然后逐渐发生代偿。一个月后,放电的平均频率恢复,但正常的单位活动和运动行为并未恢复。

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