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基于狗尾草启发的具有TiO涂层的分级表面的激光直写用于软组织防粘连

Laser Direct Writing of Setaria Virids-Inspired Hierarchical Surface with TiO Coating for Anti-Sticking of Soft Tissue.

作者信息

Zhang Qingxu, Yang Yanyan, Huo Shijie, Duan Shucheng, Han Tianao, Liu Guang, Zhang Kaiteng, Chen Dengke, Yang Guang, Chen Huawei

机构信息

School of Mechanical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China.

960 Hospital of the PLA, Tai'an 271000, China.

出版信息

Micromachines (Basel). 2024 Sep 15;15(9):1155. doi: 10.3390/mi15091155.

DOI:10.3390/mi15091155
PMID:39337815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11433979/
Abstract

In minimally invasive surgery, the tendency for human tissue to adhere to the electrosurgical scalpel can complicate procedures and elevate the risk of medical accidents. Consequently, the development of an electrosurgical scalpel with an anti-sticking coating is critically important. Drawing inspiration from nature, we identified that the leaves of Setaria Virids exhibit exceptional non-stick properties. Utilizing this natural surface texture as a model, we designed and fabricated a specialized anti-sticking surface for electrosurgical scalpels. Employing nanosecond laser direct writing ablation technology, we created a micro-nano textured surface on the high-frequency electrosurgical scalpel that mimics the structure found on Setaria Virids leaves. Subsequently, a TiO coating was deposited onto the ablated scalpel surface via magnetron sputtering, followed by plasma-induced hydrophobic modification and treatment with octadecyltrichlorosilane (OTS) to enhance the surface's affinity for silicone oil, thereby constructing a self-lubricating and anti-sticking surface. The spreading behavior of deionized water, absolute ethanol, and dimethyl silicone oil on this textured surface is investigated to confirm the effectiveness of the self-lubrication mechanism. Furthermore, the sticking force and quality are compared between the anti-sticking electrosurgical scalpel and a standard high-frequency electrosurgical scalpel to demonstrate the efficacy of the nanosecond laser-ablated micro-nano texture in preventing sticking. The findings indicate that the self-lubricating anti-sticking surface fabricated using this texture exhibits superior anti-sticking properties.

摘要

在微创手术中,人体组织粘附在电外科手术刀上的趋势会使手术过程复杂化并增加医疗事故风险。因此,开发具有防粘涂层的电外科手术刀至关重要。从自然界中获取灵感,我们发现狗尾草的叶子具有出色的不粘特性。以这种自然表面纹理为模型,我们设计并制造了一种用于电外科手术刀的特殊防粘表面。利用纳秒激光直写烧蚀技术,我们在高频电外科手术刀上创建了一个模仿狗尾草叶子结构的微纳纹理表面。随后,通过磁控溅射在烧蚀后的手术刀表面沉积TiO涂层,接着进行等离子体诱导的疏水改性并用十八烷基三氯硅烷(OTS)处理,以增强表面对硅油的亲和力,从而构建一个自润滑且防粘的表面。研究去离子水、无水乙醇和二甲基硅油在该纹理表面上的铺展行为,以确认自润滑机制的有效性。此外,对比防粘电外科手术刀和标准高频电外科手术刀之间的粘附力和质量,以证明纳秒激光烧蚀的微纳纹理在防止粘连方面的功效。研究结果表明,使用这种纹理制造的自润滑防粘表面具有卓越的防粘性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/70658f5837dd/micromachines-15-01155-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/2abb7392d428/micromachines-15-01155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/a75cc6ff8ba6/micromachines-15-01155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/c93aa833d8cc/micromachines-15-01155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/992406718e5b/micromachines-15-01155-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/9d8cfe73f1ba/micromachines-15-01155-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/1b9ad85c5d3d/micromachines-15-01155-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/8b00fa117c72/micromachines-15-01155-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/a00932e76aab/micromachines-15-01155-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/e1636e3c8bb4/micromachines-15-01155-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/70658f5837dd/micromachines-15-01155-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/2abb7392d428/micromachines-15-01155-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/a75cc6ff8ba6/micromachines-15-01155-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/c93aa833d8cc/micromachines-15-01155-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/992406718e5b/micromachines-15-01155-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/9d8cfe73f1ba/micromachines-15-01155-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/1b9ad85c5d3d/micromachines-15-01155-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/8b00fa117c72/micromachines-15-01155-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/a00932e76aab/micromachines-15-01155-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/e1636e3c8bb4/micromachines-15-01155-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9219/11433979/70658f5837dd/micromachines-15-01155-g010.jpg

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