Health Promotion and Physical Education, Wellstar College of Health and Human Services, Kennesaw State University, Kennesaw, GA 30144, USA.
Toxicology Investigators Consortium, American College of Medical Toxicology, Phoenix, AZ 85028, USA.
Int J Environ Res Public Health. 2024 Sep 21;21(9):1256. doi: 10.3390/ijerph21091256.
This study sought to determine the level of concordance between self-reported alcohol use and the presence of its urinary ethyl glucuronide (EtG) metabolite in women living in urban Kampala. In 2023, we recruited 300 young women, ages 18 to 24 years, to participate in a prospective cohort study across three sites in urban Kampala (i.e., Banda, Bwaise, and Makindye) to examine the mechanistic pathways of mental illness. As part of the baseline assessment, participants were asked to complete a research assistant-administered survey and to provide a urine sample to screen for 16 different substances and/or their metabolites, including EtG. Overall, 58% (n = 174) reported to have ever consumed alcohol and 23% (n = 68) to have used it in the past month. Among the 300 women, 10% (n = 30) had EtG levels in their urine sample and of these, 40% (n = 12) reported to have never consumed alcohol, using a self-reported survey ( = 0.035). Recent alcohol use was relatively low among the women in this study. However, the discordance between self-reported alcohol use and the presence of EtG presents concerns about the accuracy of self-reported alcohol use. Additional research is needed to contextualize self-reported alcohol use, social desirability, and the implications for alcohol prevention and intervention strategies for young women in urban Kampala.
本研究旨在确定居住在坎帕拉市区的女性自我报告的饮酒情况与尿液中乙基葡糖苷酸(EtG)代谢物的存在之间的一致性水平。2023 年,我们招募了 300 名年龄在 18 至 24 岁之间的年轻女性,在坎帕拉市区的三个地点(即班达、布瓦塞和马金迪耶)参与一项前瞻性队列研究,以研究精神疾病的发病机制。作为基线评估的一部分,参与者被要求完成一份由研究助理管理的调查,并提供尿液样本,以筛查 16 种不同的物质及其代谢物,包括 EtG。总体而言,58%(n=174)报告曾饮酒,23%(n=68)报告在过去一个月内饮酒。在 300 名女性中,10%(n=30)尿液样本中含有 EtG,其中 40%(n=12)报告从未饮酒,这与自我报告的调查结果不符(=0.035)。在这项研究中,女性近期饮酒的比例相对较低。然而,自我报告的饮酒情况与 EtG 的存在之间的不相符表明,自我报告的饮酒情况可能存在准确性问题。需要进一步研究以了解自我报告的饮酒情况、社会期望以及这对坎帕拉市区年轻女性的酒精预防和干预策略的影响。