Suppr超能文献

双相情感障碍患者需要了解的关于锂盐的知识。

What Patients with Bipolar Disorder Need to Know about Lithium.

作者信息

Post Robert M, Rybakowski Janusz K

机构信息

Bipolar Collaborative Network, Chevy Chase, MD 20815, USA.

Department of Adult Psychiatry, Poznan University of Medical Sciences, 61-701 Poznań, Poland.

出版信息

Pharmaceuticals (Basel). 2024 Sep 17;17(9):1223. doi: 10.3390/ph17091223.

Abstract

Lithium is the superior first-line treatment for bipolar disorder (BD). Yet the percentage of patients receiving lithium is abysmally low, especially in the US. Since psychiatrists have failed to place lithium in its appropriate role, we make the case that patients with BD themselves need to be better educated about the unique characteristics and pre-eminence of the drug so that it can be used more often and appropriately. Lithium has a highly unfavorable popular reputation among would-be patients and many psychiatrists. Thus, a direct appeal to patients with BD appears appropriate to try to remediate this situation. The unique assets of lithium are underappreciated or not well known. Conversely, the side effects profile of lithium are overestimated. Here, we make the case that lithium's image needs to be revised not only with better and more accurate information but also with a wholesale renaming and rebranding of the drug. We will not only outline the unique qualities and new information about the side effects of the drug but attempt to change some of the terminology conventionally used to refer to lithium so that its use may be appropriately applied earlier and at an increased frequency for patients with BD.

摘要

锂盐是双相情感障碍(BD)的首选一线治疗药物。然而,接受锂盐治疗的患者比例极低,尤其是在美国。由于精神科医生未能让锂盐发挥其应有的作用,我们认为双相情感障碍患者自身需要更好地了解这种药物的独特特性和卓越性,以便能更频繁、恰当地使用它。锂盐在潜在患者和许多精神科医生中口碑极差。因此,直接向双相情感障碍患者呼吁似乎是改善这种情况的合适做法。锂盐的独特优势未得到充分认识或广为人知。相反,锂盐的副作用却被高估了。在此,我们认为不仅需要用更好、更准确的信息,还需要对该药物进行全面的重新命名和重新定位,来修正锂盐的形象。我们不仅将概述该药物的独特性质和关于其副作用的新信息,还将尝试改变一些传统上用于指代锂盐的术语,以便能更早且更频繁地为双相情感障碍患者恰当地使用它。

相似文献

2
Overview of lithium's use: a nationwide survey.锂的使用概况:一项全国性调查。
Int J Bipolar Disord. 2021 Mar 9;9(1):10. doi: 10.1186/s40345-020-00215-z.
6
[Antipsychotics in bipolar disorders].[双相情感障碍中的抗精神病药物]
Encephale. 2004 Sep-Oct;30(5):417-24. doi: 10.1016/s0013-7006(04)95456-5.
8
Lithium Treatment Over the Lifespan in Bipolar Disorders.双相情感障碍全生命周期的锂盐治疗
Front Psychiatry. 2020 May 7;11:377. doi: 10.3389/fpsyt.2020.00377. eCollection 2020.

本文引用的文献

1
Prevention of Suicidal Behavior in Bipolar Disorder.双相情感障碍中自杀行为的预防
Focus (Am Psychiatr Publ). 2023 Oct;21(4):402-411. doi: 10.1176/appi.focus.23021025. Epub 2023 Oct 15.
2
Lithium: how low can you go?锂:你能降到多低?
Int J Bipolar Disord. 2024 Jan 30;12(1):4. doi: 10.1186/s40345-024-00325-y.
7
Lithium first: Not merely first line.锂盐优先:不仅仅是一线用药。
Bipolar Disord. 2023 Feb;25(1):7-8. doi: 10.1111/bdi.13299.
8
Long-Term Lithium Therapy: Side Effects and Interactions.长期锂盐治疗:副作用与相互作用
Pharmaceuticals (Basel). 2023 Jan 3;16(1):74. doi: 10.3390/ph16010074.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验