Evans Christopher C, Pilotte Nils, Moorhead Andrew R
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Department of Biological Sciences, Quinnipiac University, Hamden, CT 06518, USA.
Pathogens. 2024 Aug 23;13(9):714. doi: 10.3390/pathogens13090714.
Filarial nematodes of the genus include parasites that are significant to both human and veterinary medicine. Accurate diagnosis is essential for managing infections by these parasites and supporting elimination programs. Traditional diagnostic methods, such as microscopy and serology, remain vital, especially in resource-limited settings. However, advancements in molecular diagnostics, including nucleic acid amplification tests, offer enhanced sensitivity and specificity. These techniques are becoming increasingly field-friendly, expanding their applications in diagnostics. By refining existing methods, developing novel biomarkers, and understanding the zoonotic potential of various species, it is possible to improve control measures and better support elimination efforts.
该属的丝虫线虫包括对人类和兽医学都很重要的寄生虫。准确诊断对于管理这些寄生虫感染和支持消除计划至关重要。传统的诊断方法,如显微镜检查和血清学,仍然至关重要,特别是在资源有限的环境中。然而,分子诊断技术的进步,包括核酸扩增试验,提供了更高的灵敏度和特异性。这些技术正变得越来越便于现场使用,扩大了它们在诊断中的应用。通过改进现有方法、开发新的生物标志物以及了解各种物种的人畜共患病潜力,有可能改善控制措施并更好地支持消除工作。