家族性自主神经功能异常中的酪氨酸羟化酶免疫反应性
Tyrosine hydroxylase immunoreactivity in familial dysautonomia.
作者信息
Pearson J, Brandeis L, Goldstein M
出版信息
Science. 1979 Oct 5;206(4414):71-2. doi: 10.1126/science.39339.
PMID:39339
Abstract
Tyrosine hydroxylase antigen was localized immunohistochemically in sympathetic neurons from human autopsy tissue. The reaction persists in paraffin-embedded tissue, and the method is applicable to archival specimens. Increased amounts in this antigen per cell may partially compensate for decreased numbers of sympathetic neurons in familial dysautonomia.
摘要
酪氨酸羟化酶抗原通过免疫组织化学方法定位在人类尸检组织的交感神经元中。该反应在石蜡包埋组织中持续存在，且该方法适用于存档标本。在家族性自主神经功能异常中，每个细胞中该抗原量的增加可能部分补偿交感神经元数量的减少。
Zotero 插件