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凝胶化琼脂糖溶液的扩散波谱微观流变学表征

Diffusion Wave Spectroscopy Microrheological Characterization of Gelling Agarose Solutions.

作者信息

Mancebo Nuria, Rubio Ramon G, Ortega Francisco, Carbone Carlo, Guzmán Eduardo, Martínez-Pedrero Fernando, Rubio Miguel A

机构信息

Departamento de Química Física, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain.

Instituto Pluridisciplinar, Universidad Complutense de Madrid, Paseo Juan XXIII 1, 28040 Madrid, Spain.

出版信息

Polymers (Basel). 2024 Sep 16;16(18):2618. doi: 10.3390/polym16182618.

DOI:10.3390/polym16182618
PMID:39339082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11435981/
Abstract

This work investigated the gelation kinetics and mechanical properties of agarose hydrogels studied at different concentrations (in the range 1-5 g/L) and temperatures. Rheological measurements were performed by diffusing wave spectroscopy (DWS) using polystyrene and titanium dioxide particles as probes. The study emphasized the influence of gelation kinetics on the mechanical behavior of the hydrogels. The results showed that the gel properties were closely related to the thermal history and aging time of the samples. The insights gained from this study are critical for optimizing the performance of agarose hydrogels in specific applications and highlight the importance of controlling the concentration and thermal conditions during hydrogel preparation.

摘要

这项工作研究了在不同浓度（1-5 g/L范围内）和温度下琼脂糖水凝胶的凝胶化动力学和力学性能。使用聚苯乙烯和二氧化钛颗粒作为探针，通过扩散波谱（DWS）进行流变学测量。该研究强调了凝胶化动力学对水凝胶力学行为的影响。结果表明，凝胶特性与样品的热历史和老化时间密切相关。从这项研究中获得的见解对于优化琼脂糖水凝胶在特定应用中的性能至关重要，并突出了在水凝胶制备过程中控制浓度和热条件的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/9ffc9abcd0c2/polymers-16-02618-g014.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/2d7c628489c6/polymers-16-02618-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/786ac411b9b0/polymers-16-02618-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/9ffc9abcd0c2/polymers-16-02618-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/6100a60e1d2e/polymers-16-02618-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/155c56b4cf3d/polymers-16-02618-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/b4faa55aea0d/polymers-16-02618-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/d5a37bf8f5a0/polymers-16-02618-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/00d3a9771c3d/polymers-16-02618-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/a7fef7b0376d/polymers-16-02618-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/0ddda4a4ccea/polymers-16-02618-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/0c7be6c35bef/polymers-16-02618-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/5b0d06be716a/polymers-16-02618-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/8b3c84fe4fd6/polymers-16-02618-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/e7d50fbcaeb5/polymers-16-02618-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/226f5b6c43a1/polymers-16-02618-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/d819e4b8bc12/polymers-16-02618-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/f003835db1d6/polymers-16-02618-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/2d7c628489c6/polymers-16-02618-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/786ac411b9b0/polymers-16-02618-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55e0/11435981/9ffc9abcd0c2/polymers-16-02618-g014.jpg

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本文引用的文献

1
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Adv Colloid Interface Sci. 2021 Feb;288:102341. doi: 10.1016/j.cis.2020.102341. Epub 2020 Dec 13.
2
Microrheology: a review of the method and applications.微观流变学：方法与应用综述
Soft Matter. 2007 Nov 14;3(12):1449-1455. doi: 10.1039/b706004c.
3
Agarose-Based Biomaterials: Opportunities and Challenges in Cartilage Tissue Engineering.基于琼脂糖的生物材料：软骨组织工程中的机遇与挑战
Polymers (Basel). 2020 May 18;12(5):1150. doi: 10.3390/polym12051150.
4
Microrheological study of ternary surfactant-biosurfactant mixtures.三元表面活性剂-生物表面活性剂混合物的微流变研究。
Int J Cosmet Sci. 2019 Aug;41(4):364-370. doi: 10.1111/ics.12541. Epub 2019 Jun 28.
5
Microrheology, advances in methods and insights.微流变学：方法的进步与新认识。
Adv Colloid Interface Sci. 2018 Jul;257:71-85. doi: 10.1016/j.cis.2018.04.008. Epub 2018 Apr 21.
6
Hydrophobic Silica Nanoparticles Induce Gel Phases in Phospholipid Monolayers.疏水二氧化硅纳米颗粒在磷脂单层中诱导凝胶相。
Langmuir. 2016 May 17;32(19):4868-76. doi: 10.1021/acs.langmuir.6b00813. Epub 2016 May 9.
7
2D dynamical arrest transition in a mixed nanoparticle-phospholipid layer studied in real and momentum spaces.在实空间和动量空间中研究的混合纳米颗粒 - 磷脂层中的二维动态阻滞转变
Sci Rep. 2015 Dec 10;5:17930. doi: 10.1038/srep17930.
8
Particle laden fluid interfaces: dynamics and interfacial rheology.颗粒负载流体界面：动力学和界面流变学。
Adv Colloid Interface Sci. 2014 Apr;206:303-19. doi: 10.1016/j.cis.2013.10.010. Epub 2013 Oct 19.
9
Tuning of thermally induced sol-to-gel transitions of moderately concentrated aqueous solutions of doubly thermosensitive hydrophilic diblock copolymers poly(methoxytri(ethylene glycol) acrylate)-b-poly(ethoxydi(ethylene glycol) acrylate-co-acrylic acid).双重温敏两亲性嵌段共聚物聚（甲氧基三（乙二醇）丙烯酸酯）-b-聚（乙氧基二（乙二醇）丙烯酸酯-co-丙烯酸）中等浓度水溶液热诱导溶胶-凝胶转变的调谐。
J Phys Chem B. 2012 Mar 15;116(10):3125-37. doi: 10.1021/jp300298a. Epub 2012 Mar 2.
10
Dielectric and molecular dynamics study of the secondary relaxations of poly(styrene-co-methylmethacrylate) copolymers: Influence of the molecular architecture.聚（苯乙烯-共-甲基丙烯酸甲酯）共聚物二级弛豫的介电和分子动力学研究：分子结构的影响。
Eur Phys J E Soft Matter. 2011 Dec;34(12):1-14. doi: 10.1140/epje/i2011-11134-4. Epub 2011 Dec 28.