Kirsch B, Leonhardt H
Cell Tissue Res. 1979;204(1):127-40. doi: 10.1007/BF00235169.
A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar cells, ganglionic cells) of the visual pathway can be associated with retinal cells reacting positively with anti-somatostatin. In the adult rat, perikarya and processes of (i) horizontal cells, (ii) amacrine cells and (iii) large neurons in the ganglionic layer are specifically labeled. The staining of middle-sized and small ganglion cells is probably caused by the close attachment of labeled fibers to non-reacting cells. Postnatally, the immunoreactive elements develop in parallel to the differentiation of the corresponding retinal layers. It is discussed whether the three types of retinal cells containing a somatostatin-like substance provide an inhibitory system to each of the two orders of retinal neurons.
采用光镜免疫组织化学法（PAP法）在成年和幼年大鼠视网膜的核周体和细胞突起中证实了一种类生长抑素物质。这些核周体根据其大小、排列和分布得以识别。视觉通路的前两个神经元层级（感受器、双极细胞、神经节细胞）中的每一个都可能与对生长抑素抗体呈阳性反应的视网膜细胞相关。在成年大鼠中，（i）水平细胞、（ii）无长突细胞和（iii）神经节细胞层中的大神经元的核周体和突起被特异性标记。中等大小和小神经节细胞的染色可能是由于标记纤维与未反应细胞紧密附着所致。出生后，免疫反应性成分与相应视网膜层的分化同步发育。文中讨论了含有类生长抑素物质的三种视网膜细胞类型是否为视网膜神经元的两个层级中的每一个提供抑制系统。
