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男男性行为者中 HIV 自我检测的流行率:系统评价和荟萃分析的证据综合。

Prevalence of HIV Self-Testing Among Men Who Have Sex With Men: Evidence Synthesis by Systematic Review and Meta-Analysis.

机构信息

Department of Community Medicine and Family Medicine, All India Institute of Medical Science, Kalyani, India.

Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Am J Mens Health. 2024 Sep-Oct;18(5):15579883241276436. doi: 10.1177/15579883241276436.

DOI:10.1177/15579883241276436
PMID:39340385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11457272/
Abstract

HIV self-testing (HIVST) plays a significant role in addressing the health care needs of high-risk populations, particularly men who have sex with men (MSM). The present systematic review and meta-analysis provide an assessment of the prevalence of HIVST among MSM within the last 5 years. Seven databases (PubMed, Web of Science, Cochrane, Scopus, EMBASE, ProQuest, and EBSCOhost) were searched systematically from January 1, 2018 to March 10, 2023. After an independent search and quality assessment, the pooled prevalence was calculated using a random-effects model. Eight relevant studies were finally included in our study from an initial pool of 288 articles identified through a systematic search. Our meta-analysis revealed that the pooled prevalence of HIVST among MSM is 8% (95% CI: 5%-14%). Significant heterogeneity was noticed among the studies, with an value of 99% and a 95% prediction interval of 3% to 11%. Geography emerged as a significant moderator of this heterogeneity ( < .001). Specifically, studies from China reported a notably higher prevalence of 20% (15%-26%), while other countries reported a lower prevalence of 5% (3%-6%). A symmetrical Doi plot with a Luis-Furuya-Kanamori (LFK) index of -0.57 indicated no publication bias. HIVST has a low take-up among MSM globally. Factors leading to variation in HIVST need to be studied. The coordinated efforts of policymakers, health care providers, and affected communities are required in HIVST promotion.

摘要

HIV 自我检测(HIVST)在满足高风险人群,特别是男男性行为者(MSM)的医疗需求方面发挥着重要作用。本系统评价和荟萃分析评估了过去 5 年内 MSM 中 HIVST 的流行率。从 2018 年 1 月 1 日至 2023 年 3 月 10 日,系统地检索了 7 个数据库(PubMed、Web of Science、Cochrane、Scopus、EMBASE、ProQuest 和 EBSCOhost)。经过独立搜索和质量评估,使用随机效应模型计算了合并流行率。从最初通过系统搜索确定的 288 篇文章中,最终有 8 篇相关研究被纳入本研究。我们的荟萃分析显示,MSM 中 HIVST 的合并流行率为 8%(95%CI:5%-14%)。研究之间存在显著的异质性, 值为 99%,95%预测区间为 3%-11%。地理位置是这种异质性的一个显著调节因素( <.001)。具体来说,来自中国的研究报告的 HIVST 流行率显著较高,为 20%(15%-26%),而其他国家报告的流行率较低,为 5%(3%-6%)。对称的 Doi 图和 Luis-Furuya-Kanamori(LFK)指数为-0.57 表明没有发表偏倚。HIVST 在全球范围内 MSM 中的采用率较低。需要研究导致 HIVST 变化的因素。需要政策制定者、医疗保健提供者和受影响社区共同努力来推广 HIVST。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/649d8458ffe4/10.1177_15579883241276436-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/5d474e3bb002/10.1177_15579883241276436-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/6c8f1c330260/10.1177_15579883241276436-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/42a4cc2a9c18/10.1177_15579883241276436-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/649d8458ffe4/10.1177_15579883241276436-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/5d474e3bb002/10.1177_15579883241276436-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/6c8f1c330260/10.1177_15579883241276436-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/42a4cc2a9c18/10.1177_15579883241276436-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29b/11457272/649d8458ffe4/10.1177_15579883241276436-fig4.jpg

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J Med Internet Res. 2023 Apr 26;25:e46514. doi: 10.2196/46514.
2
Highlighting and addressing barriers to widespread adaptation of HIV self-testing in the United States.强调并解决阻碍 HIV 自我检测在美国广泛应用的障碍。
Expert Rev Mol Diagn. 2023 Mar;23(3):191-198. doi: 10.1080/14737159.2023.2187291. Epub 2023 Mar 8.
3
HIV Self-testing and Risk Behaviors Among Men Who Have Sex With Men in 23 US Cities, 2017.
2017 年,23 个美国城市男男性行为者的 HIV 自我检测和风险行为。
JAMA Netw Open. 2022 Dec 1;5(12):e2247540. doi: 10.1001/jamanetworkopen.2022.47540.
4
Association of anticipated HIV testing stigma and provider mistrust on preference for HIV self-testing among cisgender men who have sex with men in the Philippines.菲律宾男男性行为者对 HIV 自检偏好与预期 HIV 检测污名和提供者不信任的关联。
BMC Public Health. 2022 Dec 16;22(1):2362. doi: 10.1186/s12889-022-14834-x.
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Awareness and Use of HIV Self-Testing Among Men Who Have Sex With Men Remains Low in Spain 2 Years After Its Authorization.在西班牙,艾滋病病毒自我检测在男男性行为者中仍然知晓率和使用率低,这是在获得授权 2 年后的情况。
Front Public Health. 2022 Jun 17;10:888059. doi: 10.3389/fpubh.2022.888059. eCollection 2022.
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