Zhang Ziwei, Wang Jiawei, Li Yu, Liang Chen, Sui He, Huang Zhaoshu, Zhu Xia, Nie Lisha, Song Lingling
Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang 550001, PR China.
GE Healthcare, MR Research China, Beijing 100176, PR China.
Eur J Radiol. 2024 Dec;181:111743. doi: 10.1016/j.ejrad.2024.111743. Epub 2024 Sep 23.
To demonstrate the clinical applicability of zero echo time magnetic resonance imaging (ZTE MRI) in bone assessment of the sacroiliac joint in ankylosing spondylitis.
Between January 2021 and November 2021, twenty-one ankylosing spondylitis patients underwent clinically indicated MRI including ZTE sequence, in addition, all patients underwent a CT scan covering the sacroiliac joints within 6 months of the MRI examination. The sensitivity, specificity, and accuracy of ZTE MRI were calculated using CT as the reference standard. Cohen's κappa tests were applied to assess the agreement of positive imaging findings (including erosions, osteosclerosis, bony cystic changes, and joint space changes) between MRI and CT as well as the inter-reader agreement for the grading of sacroiliitis in AS patients.
There was no statistical significance between ZTE MRI and CT in detecting of ankylosing spondylitis(p＞0.05). The consistency of the diagnosis of positive imaging findings between ZTE MRI and CT was moderate to excellent (ranging from 0.611 to 0.889), and the consistency of the scores of positive imaging was good to excellent (ranging from 0.857 to 0.979).
ZTE MRI provides "CT-like" contrast for bony changes of the sacroiliac joint in ankylosing spondylitis and could simplify and reduce costs for some AS patients when both MRI and CT are typically required.
探讨零回波时间磁共振成像（ZTE MRI）在强直性脊柱炎骶髂关节骨质评估中的临床应用价值。
2021年1月至2021年11月，21例强直性脊柱炎患者接受了包括ZTE序列在内的临床指征性MRI检查，此外，所有患者在MRI检查后6个月内接受了覆盖骶髂关节的CT扫描。以CT为参考标准，计算ZTE MRI的敏感性、特异性和准确性。应用Cohen's κappa检验评估MRI与CT之间阳性影像学表现（包括侵蚀、骨质硬化、骨囊性改变和关节间隙改变）的一致性，以及AS患者骶髂关节炎分级的阅片者间一致性。
ZTE MRI与CT在强直性脊柱炎检测方面无统计学差异（p＞0.05）。ZTE MRI与CT之间阳性影像学表现诊断的一致性为中度至高度（范围为0.611至0.889），阳性影像学评分的一致性为良好至高度（范围为0.857至0.979）。
ZTE MRI为强直性脊柱炎骶髂关节的骨质改变提供了“类似CT”的对比，对于一些通常需要同时进行MRI和CT检查的AS患者，可简化检查并降低成本。
