治疗性合成阴离子转运体。
Therapeutic synthetic anion transporters.
机构信息
School of Physical and Mathematical Sciences, Faculty of Science, University of Technology Sydney, Ultimo 2007, NSW, Australia.
School of Physical and Mathematical Sciences, Faculty of Science, University of Technology Sydney, Ultimo 2007, NSW, Australia.
出版信息
Curr Opin Chem Biol. 2024 Dec;83:102535. doi: 10.1016/j.cbpa.2024.102535. Epub 2024 Sep 27.
This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. This includes anionophores with antibiotic or antifungal activity, anticancer activity, or the potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted anion transporters are also discussed.
本文简要综述了近期文献报道的具有潜在生物学活性的小分子阴离子转运体的相关内容，其中包括具有抗生素或抗真菌、抗癌活性，或有望治疗囊性纤维化等通道病的阴离子载体，此外还讨论了选择性和靶向性阴离子转运体。
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