Tunac J B, Underhill M
J Antibiot (Tokyo). 1985 Oct;38(10):1344-9. doi: 10.7164/antibiotics.38.1344.
2'-Chloropentostatin (2-CP) is a new nucleoside antibiotic produced by Actinomadura sp. ATCC 39365. A selectively sensitive assay organism, Enterococcus faecalis PD 05045 (MIC 0.005 micrograms/ml) was instrumental in the discovery of this compound. 2-CP is a tight-binding inhibitor of adenosine deaminase (Ki = 1.1 X 10(-10) M).
2'-氯喷司他丁（2-CP）是由马杜拉放线菌ATCC 39365产生的一种新型核苷类抗生素。一种选择性敏感的检测生物——粪肠球菌PD 05045（最低抑菌浓度为0.005微克/毫升）在该化合物的发现过程中发挥了重要作用。2-CP是腺苷脱氨酶的紧密结合抑制剂（抑制常数Ki = 1.1×10⁻¹⁰ M）。
