Department of Hospital Medicine, Cleveland Clinic Lerner College of Medicine, Integrated Hospital Care Institute, Cleveland Clinic, 9500 Euclid Avenue, M2 Annex, Cleveland, OH 44195, USA.
Department of Hospital Medicine, Cleveland Clinic Lerner College of Medicine, Integrated Hospital Care Institute, Cleveland Clinic, 9500 Euclid Avenue, M2 Annex, Cleveland, OH 44195, USA.
Med Clin North Am. 2024 Nov;108(6):1135-1153. doi: 10.1016/j.mcna.2024.05.002. Epub 2024 Aug 1.
Medication management in the perioperative period is a critical part of the decision-making prior to surgery. While randomized trial levels of evidence in this space are scant, retrospective data and expert consensus provide practical guidance for these decisions. Clinicians must understand risks and benefits of withholding versus continuing medications, stop medications based on pharmacokinetics and effect on primary disease and surgical risk, and resume medications after surgery in a timely manner. Knowing alternate routes of medication administration can help keep chronic disease processes stable through surgery.
围手术期的药物管理是手术前决策的关键部分。虽然这方面的随机试验证据水平很少，但回顾性数据和专家共识为这些决策提供了实用指导。临床医生必须了解停药与继续用药的风险和益处，根据药代动力学和对主要疾病及手术风险的影响来停止用药，并在手术后及时恢复用药。了解替代的药物给药途径有助于在手术期间保持慢性疾病过程的稳定。
