Mingels Clemens, Chung Kevin J, Pantel Austin R, Rominger Axel, Alberts Ian, Spencer Benjamin A, Nardo Lorenzo, Pyka Thomas
Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department of Radiology, University of California Davis, Sacramento, CA.
Department of Radiology, University of California Davis, Sacramento, CA.
Semin Nucl Med. 2025 Jan;55(1):21-30. doi: 10.1053/j.semnuclmed.2024.08.003. Epub 2024 Sep 27.
Long-axial field-of-view (LAFOV) systems have changed the field of molecular imaging. Since their introduction, many PET centers have installed these next-generation digital systems to provide more detailed imaging and acquire PET images in a single bed position. Indeed, vertex to thigh imaging for oncological indications can be obtained in most of the population with the currently available LAFOV systems. Moreover, Total Body (TB) PET, a subtype of LAFOV, enables imaging the entire patient-from vertex through the toes-with one bed-position for most of the population. This review aims to identify possible challenges and opportunities for PET-centers working with TB and LAFOV systems. Emphasis is placed on the strength and weaknesses in clinical routine of currently available and upcoming TB and LAFOV PET systems.
长轴视野（LAFOV）系统改变了分子成像领域。自引入以来，许多PET中心已安装这些下一代数字系统，以提供更详细的成像，并在单个床位获取PET图像。事实上，使用目前可用的LAFOV系统，大多数人群都可以获得针对肿瘤适应症的从头顶到大腿的成像。此外，LAFOV的一种亚型——全身（TB）PET，能够在大多数人群中通过一个床位对整个患者进行成像，即从头顶到脚趾。本综述旨在确定使用TB和LAFOV系统的PET中心可能面临的挑战和机遇。重点关注当前可用的和即将推出的TB和LAFOV PET系统在临床常规中的优缺点。
