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缺血与再灌注期间心室颤动的优势频率。

Dominant Frequency of Ventricular Fibrillation During Ischemia and Reperfusion.

机构信息

Saint-Petersburg State Research Institute of Phthisiopulmonology, Ministry of Health of the Russian Federation, St. Petersburg, Russia.

Saint-Petersburg State University, St. Petersburg, Russia.

出版信息

Bull Exp Biol Med. 2024 Sep;177(5):584-587. doi: 10.1007/s10517-024-06228-3. Epub 2024 Sep 28.

DOI:10.1007/s10517-024-06228-3
PMID:39342005
Abstract

Ventricular fibrillation (VF) in dogs is characterized by a rapid increase in its dominant frequency during the 1st minute of reperfusion followed by its decrease during the 2nd minute of reperfusion. The longer is ischemia in VF, the greater is the increase in dominant VF frequency during reperfusion. The 1st minute of reperfusion is characterized by a 1.2-fold increase in dominant VF frequency after 1-min ischemia in VF, by 1.4-fold increase after 2-min ischemia, by 2-fold increase after 3 min, and by 2.6-fold increase after 4-min ischemia. During the 2nd minute of reperfusion, the dominant VF frequency decreased by 1.1-1.3 times, and during 3rd-10th minutes of reperfusion, the dominant VF frequency is stabilized.

摘要

犬心室颤动(VF)的特征是在再灌注的第 1 分钟内其主导频率迅速增加,随后在再灌注的第 2 分钟内降低。VF 缺血时间越长,再灌注期间主导 VF 频率的增加越大。在再灌注的第 1 分钟内,在 VF 缺血 1 分钟后,主导 VF 频率增加 1.2 倍,缺血 2 分钟后增加 1.4 倍,缺血 3 分钟后增加 2 倍,缺血 4 分钟后增加 2.6 倍。在再灌注的第 2 分钟内,主导 VF 频率降低 1.1-1.3 倍,在再灌注的第 3-10 分钟内,主导 VF 频率稳定。

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本文引用的文献

1
Ventricular Arrhythmias in First Acute Myocardial Infarction: Epidemiology, Mechanisms, and Interventions in Large Animal Models.首次急性心肌梗死中的室性心律失常:大型动物模型中的流行病学、机制及干预措施
Front Cardiovasc Med. 2019 Nov 5;6:158. doi: 10.3389/fcvm.2019.00158. eCollection 2019.
2
Effects of combination of sotalol and verapamil on initiation, maintenance, and termination of ventricular fibrillation in swine hearts.索他洛尔和维拉帕米联合对猪心室颤动的起始、维持和终止的影响。
Cardiovasc Ther. 2018 Jun;36(3):e12326. doi: 10.1111/1755-5922.12326. Epub 2018 Mar 25.
3
Endocardial Activation Drives Activation Patterns During Long-Duration Ventricular Fibrillation and Defibrillation.
心内膜激活驱动长时程室颤和除颤期间的激活模式。
Circ Arrhythm Electrophysiol. 2017 Dec;10(12). doi: 10.1161/CIRCEP.117.005562.
4
Human ventricular fibrillation during global ischemia and reperfusion: paradoxical changes in activation rate and wavefront complexity.人心室颤动在全球缺血和再灌注期间:激动率和波阵面复杂性的矛盾变化。
Circ Arrhythm Electrophysiol. 2011 Oct;4(5):684-91. doi: 10.1161/CIRCEP.110.961284. Epub 2011 Aug 13.