通过反应性添加免疫调节剂克服抗TNF治疗的免疫原性。 - Suppr

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超能文献

Overcoming Immunogenicity to Anti-TNF Therapy by Reactively Adding an Immunomodulator.

作者信息

Ward Mark G

机构信息

Alfred Hospital, Melbourne, Australia.

Central Clinical School, Monash University, Melbourne, Australia.

出版信息

Dig Dis Sci. 2024 Oct;69(10):3606-3607. doi: 10.1007/s10620-024-08620-5. Epub 2024 Sep 28.

DOI:10.1007/s10620-024-08620-5

PMID:39342065

Abstract

摘要

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Dig Dis Sci. 2024 Oct;69(10):3920-3931. doi: 10.1007/s10620-024-08515-5. Epub 2024 Jun 14.

HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases.HLA-DQ2与免疫介导的炎症性疾病患者中抗英夫利昔单抗抗体的形成有关。

J Intern Med. 2023 May;293(5):648-655. doi: 10.1111/joim.13616. Epub 2023 Feb 26.

Dashboard-Driven Accelerated Infliximab Induction Dosing Increases Infliximab Durability and Reduces Immunogenicity.仪表盘驱动的英夫利昔单抗加速诱导剂量可提高英夫利昔单抗的持久性并降低免疫原性。

Inflamm Bowel Dis. 2022 Sep 1;28(9):1375-1385. doi: 10.1093/ibd/izab285.

Addition of azathioprine to the switch of anti-TNF in patients with IBD in clinical relapse with undetectable anti-TNF trough levels and antidrug antibodies: a prospective randomised trial.在抗 TNF 治疗的 IBD 患者临床复发时，即使抗 TNF 药物浓度和抗药抗体检测不到，加用硫唑嘌呤转换方案：一项前瞻性随机试验。

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Immunogenicity of biologics in inflammatory bowel disease.生物制剂在炎症性肠病中的免疫原性。

Therap Adv Gastroenterol. 2018 Jan 21;11:1756283X17750355. doi: 10.1177/1756283X17750355. eCollection 2018.

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