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达芬奇机器人手术与胸腔镜手术治疗不同体质量指数纵隔肿瘤患者的疗效:一项多中心倾向评分匹配研究。

Efficacy of the da Vinci robot versus thoracoscopic surgery for patients with mediastinal tumors of different body mass index: a multicenter propensity score-matched study.

机构信息

Department of thoracic surgery, The Affiliated Huizhou Hospital, Guangzhou Medical University, Huizhou, China.

Department of thoracic surgery, Second Hospital of Lanzhou University, Lanzhou, China.

出版信息

World J Surg Oncol. 2024 Sep 28;22(1):257. doi: 10.1186/s12957-024-03542-y.

Abstract

BACKGROUND

The purpose of the present study was to evaluate the efficacy and safety of da Vinci robot-assisted thoracoscopic surgery (RATS) versus video-assisted thoracoscopic surgery (VATS) for the treatment of patients with mediastinal tumors of different body mass indices (BMI).

METHODS

A retrospective cohort study was used to collect 260 patients with mediastinal tumors admitted to three medical centers in China from December 2020 to March 2024. These patients underwent mediastinal tumor resection by RATS (n = 125) or VATS (n = 135). Propensity score matching (PSM) analysis was performed for the both groups, and further, the patients were divided into the N-BMI group (18.5 kg/m ≤ BMI < 25 kg/m) and the H-BMI group (BMI ≥ 25 kg/m) based on their BMI to compare patients' surgery-related information.

RESULTS

The RATS group had more advantages than the VATS group in terms of intraoperative blood loss, total postoperative drainage, postoperative drainage time, and postoperative hospital stay. As for hospitalization costs, the VATS group was more advantageous. In the H-BMI group, subgroup analysis showed a statistically significant difference in shorter operative time and lower incidence of postoperative complications in the RATS group.

CONCLUSION

RATS has technical and short-term efficacy advantages in comparison with VATS, although it has the drawback of high costs associated with the treatment of mediastinal tumors. In the patients with mediastinal tumors of H-BMI, RATS can achieve better short-term outcomes and safety, especially in the reduction of the incidence of postoperative complications.

摘要

背景

本研究旨在评估达芬奇机器人辅助胸腔镜手术(RATS)与电视辅助胸腔镜手术(VATS)治疗不同体质量指数(BMI)纵隔肿瘤患者的疗效和安全性。

方法

采用回顾性队列研究,收集 2020 年 12 月至 2024 年 3 月中国 3 家医疗中心收治的 260 例纵隔肿瘤患者资料,其中 125 例行 RATS 纵隔肿瘤切除术(RATS 组),135 例行 VATS 纵隔肿瘤切除术(VATS 组)。对两组患者进行倾向评分匹配(PSM)分析,根据 BMI 将患者进一步分为 N-BMI 组(18.5kg/m2≤BMI<25kg/m2)和 H-BMI 组(BMI≥25kg/m2),比较患者手术相关信息。

结果

RATS 组术中出血量、总术后引流量、术后引流时间和术后住院时间均优于 VATS 组。而在住院费用方面,VATS 组更具优势。在 H-BMI 组中,亚组分析显示 RATS 组手术时间更短,术后并发症发生率更低,差异有统计学意义。

结论

与 VATS 相比,RATS 在技术和短期疗效方面具有优势,尽管治疗纵隔肿瘤的费用较高。对于 H-BMI 纵隔肿瘤患者,RATS 可以达到更好的短期疗效和安全性,特别是降低术后并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950d/11439245/0b0915d06b74/12957_2024_3542_Fig1_HTML.jpg

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