Sadi Konuk Training and Research Hospital, Department of Orthopedics and Traumatology, Bakırköy/Istanbul, Turkey.
University of Health Sciences, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Department of Orthopedics and Traumatology, Bakırköy/Istanbul, Turkey.
Acta Chir Orthop Traumatol Cech. 2024;91(4):245-247. doi: 10.55095/ACHOT2024/033.
Heterotopic ossification (HO) denotes aberrant osteogenesis in extra-skeletal tissues, often associated with neurological disorders, total hip arthroplasty, and specific traumatic scenarios. Neurogenic heterotopic ossification manifests prominently subsequent to traumatic brain injury or spinal cord injury, with Guillain-Barre Syndrome presenting an infrequent etiological link. This article details the case of a 56-year-old female diagnosed with Guillain-Barre Syndrome, who developed neurogenic heterotopic ossification around both hips within two years of disease onset. The patient's medical history included mechanical ventilation, incomplete tetraplegia, and prolonged immobilization. A conclusive diagnosis of HO was established through radiological and clinical assessments. After neurogenic heterotopic ossification was confirmed, the patient had surgery to remove the lesions, radiation therapy, and medication treatments as planned. Physical therapy was introduced one week post-surgery, with subsequent follow-ups tracking improvements in pain levels, range of motion (ROM), and Activities of Daily Living scores. Key words: neurogenic heterotopic ossification, Guillain-Barre syndrome, hip, excision.
异位骨化（HO）是指骨骼外组织异常成骨，常与神经紊乱、全髋关节置换术和特定创伤情况相关。神经源性异位骨化主要发生在创伤性脑损伤或脊髓损伤后，吉兰-巴雷综合征则是一种罕见的病因。本文详细介绍了一例 56 岁女性病例，该患者诊断为吉兰-巴雷综合征，在发病两年内双侧髋关节周围发生神经源性异位骨化。患者既往有机械通气、不完全性四肢瘫痪和长时间固定的病史。HO 的明确诊断是通过影像学和临床评估确定的。神经源性异位骨化确诊后，患者按计划接受了手术切除、放疗和药物治疗。术后一周开始物理治疗，随后的随访评估疼痛水平、活动范围（ROM）和日常生活活动评分的改善情况。关键词：神经源性异位骨化；吉兰-巴雷综合征；髋关节；切除术。
