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涎腺分泌性癌:一例小涎腺病例报告并文献复习

Salivary gland secretory carcinoma: A case presentation in minor salivary gland with review.

作者信息

de Souza Tolentino Elen, Jacomacci Willian Pecin, Camarini Camila, Sedassari Bruno Tavares, de Miranda Fabio Vieira, Cardoso Camila Lopes

机构信息

Department of Dentistry, State University of Maringa, Maringá, Paraná, Brazil.

Department of Medical Sciences, University of São Paulo, São Paulo, São Paulo, Brazil.

出版信息

J Stomatol Oral Maxillofac Surg. 2025 Jun;126(3):102096. doi: 10.1016/j.jormas.2024.102096. Epub 2024 Sep 28.

Abstract

INTRODUCTION AND IMPORTANCE

Salivary gland secretory carcinoma (SGSC) represents a rare malignant tumor of the salivary glands. Despite being regarded as low-grade tumors, they may manifest with metastases and a high-grade aggressive clinical behaviour. The literature on this subject is limited, and there is currently no standardized approach to treatment.

CASE REPORT

We report a rare case of SGSC in the palate of a 14-year-old female patient. The patient underwent excision, bilateral tonsillectomy and adjuvant radiotherapy.

CLINICAL DISCUSSION

A critical review of the literature was conducted with the objective of analysing the cases of intraoral SGSC that have been previously reported. A total of 23 articles, published between 2010 and 2024, were identified as being directly pertinent to the review, resulting in a total of 58 patients being included.

CONCLUSION

SGSC on the hard palate in a 14-year-old child is an exceedingly rare occurrence. These tumors can mimic other pathologies of the salivary glands clinically and microscopically, which can result in misdiagnosis and a delay in treatment.

摘要

引言与重要性

涎腺分泌癌(SGSC)是一种罕见的涎腺恶性肿瘤。尽管被视为低级别肿瘤,但它们可能出现转移并具有高级别的侵袭性临床行为。关于该主题的文献有限,目前尚无标准化的治疗方法。

病例报告

我们报告了一例罕见的14岁女性患者腭部涎腺分泌癌病例。该患者接受了切除手术、双侧扁桃体切除术及辅助放疗。

临床讨论

对文献进行了批判性综述,目的是分析先前报道的口腔内涎腺分泌癌病例。共确定了2010年至2024年间发表的23篇文章与该综述直接相关,共纳入58例患者。

结论

14岁儿童硬腭部的涎腺分泌癌极为罕见。这些肿瘤在临床和显微镜下可模仿涎腺的其他病变,可能导致误诊和治疗延迟。

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