Kobayashi Akira, Hayashi Takahiko, Igarashi Ami, Shimizu Toshiki, Yokogawa Hideaki, Yuda Kentaro, Bachmann Björn, Yamagami Satoru, Sugiyama Kazuhisa
Department of Ophthalmology, Kanazawa University Hospital, Ishikawa, Japan.
Department of Ophthalmology and Department of Visual Sciences, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Int Med Case Rep J. 2024 Sep 25;17:795-800. doi: 10.2147/IMCRJ.S482261. eCollection 2024.
Currently, the push-in technique through the corneal tunnel using a blunt-tip spatula is used to insert an artificial corneal endothelium (EndoArt) into the anterior chamber (AC). The device is useful for patients with bullous keratopathy; however, it may be difficult to manipulate the very thin implant through hazy cornea. Unlike DMEK graft, it cannot be stained and the F-mark is faint. So, visualizing and orienting the implant is a real challenge especially through a hazy cornea and inadequate AC visualization. Therefore, alternative EndoArt implantation techniques are needed in patients with advanced endothelial dysfunction to avoid complications.
To report an alternative technique for EndoArt implantation using a Busin glide.
The EndoArt was loaded onto the Busin glide with the concave side of the EndoArt facing upward and was then pulled/pushed into the Busin glide opening. After the Descemet's membrane and endothelium were detached and removed in a circular fashion in a patient with advanced corneal endothelial decompensation, the Busin glide was inserted into the corneal incision, and the EndoArt was slowly pulled into the AC using retractor forceps. Finally, the air was injected into the AC.
The Busin glide-assisted pull-through technique smoothly and securely inserted the EndoArt into the AC without upside-down attachment. This alternative technique can be useful for patients with a history of repeat intraocular surgeries or trauma with severe corneal edema to avoid potential complications such as epithelial implantation cysts or downgrowth.
目前,使用钝头刮铲经角膜隧道的推注技术用于将人工角膜内皮(EndoArt)植入前房(AC)。该装置对大疱性角膜病变患者有用;然而,通过混浊角膜操作非常薄的植入物可能很困难。与角膜后弹力层内皮移植术(DMEK)移植物不同,它不能染色且F标记模糊。因此,尤其是通过混浊角膜且前房可视化不足时,可视化和定位植入物是一项真正的挑战。所以,对于晚期内皮功能障碍患者需要替代的EndoArt植入技术以避免并发症。
报告一种使用Busin滑行器进行EndoArt植入的替代技术。
将EndoArt装载到Busin滑行器上,EndoArt的凹面向上,然后将其拉入/推至Busin滑行器开口处。在一名晚期角膜内皮失代偿患者中以环形方式分离并移除后弹力层和内皮后,将Busin滑行器插入角膜切口,并用牵开钳将EndoArt缓慢拉入前房。最后,向前房注入空气。
Busin滑行器辅助的拉入技术可顺利、安全地将EndoArt植入前房,且不会出现倒置附着。这种替代技术对有多次眼内手术史或伴有严重角膜水肿外伤的患者可能有用,可避免诸如上皮植入囊肿或内生等潜在并发症。