Jakhar Ashima, Vats Anjali Shrivastava, Singh Simarjeev, Thind Gagandeep, Aga Nausheen, Agwan Muhammad Atif Saleem, Makkad Ramanpal Singh
Bharati Vidyapeeth Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Department of Conservative Dentistry and Endodontics, Gian Sagar Dental College and Hospital, Rajpura, Patiala, Punjab, India.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2306-S2308. doi: 10.4103/jpbs.jpbs_169_24. Epub 2024 Jul 18.
Both the mechanical cleansing effect and the irrigants' capacity to disintegrate tissue are necessary for irrigation to be successful. Strong antibacterial but not poisonous to the periapical tissues and increased pulp tissue dissolution irrigant are all desirable qualities in an irrigant.
To assess and compare the antibacterial properties and pulp tissue dissolving activity of various irrigation solutions.
A total of 240 human mandibular permanent premolar teeth that were extracted recently for periodontal or orthodontic reasons were used in this investigation. Following irrigation, blood agar plates were used to conduct colony-forming unit (CFU) counts of the microorganism breeding colonies. Next, log CFU was computed. Before evaluating the ability of the five distinct irrigants utilized in this investigation to dissolve the frozen pulp tissues, the tissues were first smashed into smaller pieces using a mallet.
The bacterial count after irrigation in category 1 (normal saline), category 2 (aqueous ozone), category 3 (ethylenediaminetetraacetic acid (EDTA)), category 4 (chlorhexidine gluconate (CHX)), category 5 (super-oxidized water), and category 6 (sodium hypochlorite (NaOCl)) was 6.08 ± 0.87 log CFU mL, 0.92 ± 0.89 log CFU mL, 4.15 ± 0.20 log CFU mL, 3.34 ± 0.46 log CFU mL, 0.21 ± 0.52 log CFU mL, and 0.00 ± 0.00 log CFU mL, respectively.
NaOCl has maximum antimicrobial reduction and pulp tissue dissolution property.
冲洗成功既需要机械清洁作用，也需要冲洗剂分解组织的能力。冲洗剂应具备强效抗菌且对根尖周组织无毒以及增强牙髓组织溶解的特性。
评估和比较不同冲洗液的抗菌性能和牙髓组织溶解活性。
本研究共使用了240颗因牙周或正畸原因近期拔除的人类下颌恒前磨牙。冲洗后，使用血琼脂平板对微生物繁殖菌落进行菌落形成单位（CFU）计数。接着，计算log CFU。在评估本研究中使用的五种不同冲洗剂溶解冷冻牙髓组织的能力之前，先用木槌将组织敲成小块。
第1类（生理盐水）、第2类（臭氧水溶液）、第3类（乙二胺四乙酸（EDTA））、第4类（葡萄糖酸氯己定（CHX））、第5类（超氧化水）和第6类（次氯酸钠（NaOCl））冲洗后的细菌计数分别为6.08±0.87 log CFU/mL、0.92±0.89 log CFU/mL、4.15±0.20 log CFU/mL、3.34±0.46 log CFU/mL、0.21±0.52 log CFU/mL和0.00±0.00 log CFU/mL。
NaOCl具有最大的抗菌减少和牙髓组织溶解性能。
