Xu Thomas O, Levitt Marc A, Feng Christina
Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia, USA.
World J Pediatr Surg. 2024 Sep 25;7(3):e000887. doi: 10.1136/wjps-2024-000887. eCollection 2024.
The treatment of Hirschsprung disease (HSCR) is surgical resection of aganglionic bowel and subsequent pull-through of ganglionated bowel. Despite many advances since the initial description of the disease and its surgical management more than half a century ago, there remain considerable controversies regarding the history of the surgical technique, the optimal timing of the primary and multistage pull-through, the best treatment for patients with a delayed diagnosis of HSCR, and the management of post pull-through complications such as soiling due to sphincter incompetence, the presence of a transition zone, and the prevention of enterocolitis. The following review will explore each of these controversies.
先天性巨结肠(HSCR)的治疗方法是手术切除无神经节肠段,随后将有神经节的肠段拖出。尽管自半个多世纪前首次描述该疾病及其手术治疗以来已有许多进展,但在手术技术的历史、一期和分期拖出术的最佳时机、HSCR延迟诊断患者的最佳治疗方法以及拖出术后并发症(如因括约肌功能不全导致的便污、过渡区的存在以及预防小肠结肠炎)的处理等方面仍存在相当大的争议。以下综述将探讨这些争议中的每一个。