Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Tremor Other Hyperkinet Mov (N Y). 2024 Sep 25;14:49. doi: 10.5334/tohm.948. eCollection 2024.
There are myths and misperceptions about most human diseases, and neurological diseases are no exception. In many instances, myths and misconceptions reflect what is no more than the collective failure of the field to catch up with the state of the science in that field. Hence, one may perhaps refer to these as "lags" rather than myths. As the field of medicine attempts to be evidence-based, it is best to remain true to published data and the state of the science. In this paper, I review six myths and misconceptions about ET. Myth 1 relates to the natural history and prognosis of ET. Myths 2 and 3 relate to the biological basis of ET, whereas myths 4 and 5 relate to the expression of the core clinical feature of ET. Finally, myth 6 focuses on the issue of disease classification. The myths are as follows: "ET is not associated with a shorter life expectancy". "The pathophysiology of ET remains unclear". "There have also been studies that do not show any cerebellar degeneration". "ET is a postural or a kinetic tremor". "Action tremor in ET is usually bilateral and symmetric". "ET plus". As neurologists, we are not ignorant of feedback loops. A regular review of facts should help to frame one's output. As such, one's formulations and output will be firmly grounded in data.
关于大多数人类疾病都存在一些误解和误解,神经疾病也不例外。在许多情况下,误解和误解反映的只不过是该领域未能跟上该领域科学发展的状态。因此,人们也许可以将这些称为“滞后”而不是误解。随着医学领域试图基于证据,最好还是要坚持发表的数据和科学现状。在本文中,我回顾了关于 ET 的六个误解和误解。第一个误解与 ET 的自然病史和预后有关。第二个和第三个误解与 ET 的生物学基础有关,而第四个和第五个误解与 ET 的核心临床特征的表达有关。最后,第六个神话集中在疾病分类问题上。这些神话如下:“ ET 与预期寿命缩短无关”。“ ET 的病理生理学仍不清楚”。“也有研究表明没有小脑变性”。“ ET 是姿势性或动力性震颤”。“ ET 中的动作震颤通常是双侧对称的”。“ ET 加”。作为神经科医生,我们并不无视反馈回路。定期检查事实应有助于形成自己的输出。因此,人们的表述和输出将牢固地基于数据。