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上皮样炎性肌纤维母细胞肉瘤:1例罕见病例报告

Epithelioid Inflammatory Myofibroblastic Sarcoma: A Report of a Rare Case.

作者信息

Ronanki Varun, Tejeswini Vaddatti, Venkata Renuka Inuganti, Raheema Shaik, S K Kanth Bakkamanthala

机构信息

Pathology, NRI Medical College, Guntur, IND.

出版信息

Cureus. 2024 Aug 30;16(8):e68184. doi: 10.7759/cureus.68184. eCollection 2024 Aug.

Abstract

Epithelioid inflammatory myofibroblastic sarcoma (EIMS), a variant of inflammatory myofibroblastic tumor (IMT), is a rare malignant tumor commonly associated with anaplastic lymphoma kinase (ALK) gene fusions and is aggressive in nature with local recurrence. Here, we report a case of a 23-year-old female who presented with a cough and, upon investigations, was found to have a mass in the left upper lobe of the lung detected by chest computed tomography (CT). Biopsy revealed EIMS with ALK and desmin protein expression. The patient underwent a lobectomy via video-assisted thoracoscopic surgery (VATS). The postoperative period was uneventful.

摘要

上皮样炎性肌纤维母细胞肉瘤(EIMS)是炎性肌纤维母细胞瘤(IMT)的一种变体,是一种罕见的恶性肿瘤,通常与间变性淋巴瘤激酶(ALK)基因融合相关,具有侵袭性,易局部复发。在此,我们报告一例23岁女性病例,该患者因咳嗽就诊,经检查,胸部计算机断层扫描(CT)发现左肺上叶有一肿块。活检显示为伴有ALK和结蛋白蛋白表达的EIMS。患者接受了电视辅助胸腔镜手术(VATS)下的肺叶切除术。术后恢复顺利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7591/11439187/d83f528e6d7f/cureus-0016-00000068184-i01.jpg

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