Sun Dianrong, Zhao Jianhui, Zhang Leihong, Yu Rong, Hou Mei
Department of Neurorehabilitation Qingdao University Affiliated Qingdao Women and Children's Hospital Shandong China.
Pediatr Investig. 2024 Jul 31;8(3):177-183. doi: 10.1002/ped4.12444. eCollection 2024 Sep.
Viral encephalitis is one of the main causes of the perisylvian syndrome, which can cause damage to children's language-speech, feeding, and swallowing functions. Comprehensive assessment of language-speech and swallowing function and comorbidity research on these children will help children's rehabilitation workers to better understand the disease and strengthen the systematic management of comorbid disorders.
To describe speech and language pathology and the occurrence of comorbid disorders in children with perisylvian syndrome induced by viral encephalitis.
Twenty-two children with acquired perisylvian syndrome were recruited in this study. Language and speech functions, including oral motor function, swallowing function, language ability, and dysarthria were assessed in these patients. Craniocerebral magnetic resonance imaging (MRI), electroencephalogram examination, and intelligence evaluation were performed to determine brain lesions and comorbid disorders.
All children exhibited different degrees of oral movement, dysphagia, and speech and language disorders. There was a significant difference between expressive and receptive language ability ( < 0.05). There were 10, 8, and 12 children who had an intellectual disability, limb disability, and epilepsy, respectively. In addition to the damage of the peri-tegmental cortex found in MRI, thalamus lesions occurred in 19 cases and white matter involvement in six cases.
Children with acquired perisylvian syndrome caused by viral encephalitis are characterized by persistent pseudobulbar dysfunction, speech and language impairment, and orofacial diplegia. They have a high probability of secondary epilepsy and are prone to motor and cognitive impairment, which need systematic management.
病毒性脑炎是大脑外侧裂周综合征的主要病因之一，可导致儿童语言、进食和吞咽功能受损。对这些儿童的语言和吞咽功能进行综合评估以及合并症研究，将有助于儿童康复工作者更好地了解该疾病，并加强对合并症的系统管理。
描述病毒性脑炎所致大脑外侧裂周综合征患儿的言语病理学及合并症的发生情况。
本研究纳入22例获得性大脑外侧裂周综合征患儿。对这些患儿进行语言和言语功能评估，包括口腔运动功能、吞咽功能、语言能力和构音障碍。进行颅脑磁共振成像（MRI）、脑电图检查和智力评估，以确定脑损伤和合并症。
所有患儿均表现出不同程度的口腔运动、吞咽困难以及言语和语言障碍。表达性和接受性语言能力之间存在显著差异（<0.05）。分别有10例、8例和12例患儿存在智力残疾、肢体残疾和癫痫。除MRI发现的被盖周皮质损伤外，19例出现丘脑病变，6例出现白质受累。
病毒性脑炎所致获得性大脑外侧裂周综合征患儿的特征为持续性假性延髓功能障碍、言语和语言障碍以及口面部双侧瘫。他们继发癫痫的可能性高，且易出现运动和认知障碍，需要进行系统管理。
