Cartilage and osteoarthrosis: changes of collagen and proteoglycans.
作者信息
Adam M, Musilová J
出版信息
Czech Med. 1979;2(1-2):64-8.
PMID:393478
Abstract
The authors discuss changes of proteoglycans and collagen in osteoarthrotic cartilage, based on their own results. During osteoarthrosis the proteoglycan molecule diminishes in size, mainly due to a diminution of the carbohydrate portion. The diminution of binding glycoprotein leads to changes in the interaction with hyaluronic acid. Collagen is more soluble and has a reduced resistance to proteolytic enzymes. In the osteoarthrotic cartilage also collagen type I and III is present.
摘要
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