1例儿童急性髓系白血病M2亚型异基因造血干细胞移植后因HHV-6脑炎导致视力损害的病例。
A case of visual impairment due to HHV-6 encephalitis after allogeneic hematopoietic stem cell transplantation in childhood acute myeloid leukemia-M2 subtype.
作者信息
Pan Yan-Sha, Li Hao, Yang Min, Zhang Chang-Ling, Xiao Lan, Liu Chun-Yan, Deng Xue-Yan, Xu Xiu-Mei, Yang You, Liu Wen-Jun
机构信息
Department of Pediatrics (Children Hematological Oncology), Childhood Hematological Oncology and Birth Defects Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Sichuan Clinical Research Center for Birth Defects, Luzhou, Sichuan, China.
出版信息
Ann Hematol. 2024 Dec;103(12):5973-5979. doi: 10.1007/s00277-024-06030-1. Epub 2024 Sep 30.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a crucial treatment option for children with M2 subtype acute myeloid leukemia (AML). Human herpesvirus 6 (HHV-6) encephalitis following transplantation is a rare postoperative complication, with a poor prognosis and a high fatality rate in allo-HSCT recipients. In this report, a juvenile patient with AMLwas successfully treated after developing visual impairment as a result of HHV-6B encephalitis during allo-HSCT therapy. HHV-6 encephalitis-associated visual impairment after transplantation is rare, and clinical diagnosis and treatment are challenging, requiring more attention in the future.
异基因造血干细胞移植（allo-HSCT）是M2亚型急性髓系白血病（AML）患儿的关键治疗选择。移植后人类疱疹病毒6型（HHV-6）脑炎是一种罕见的术后并发症，在allo-HSCT受者中预后较差且死亡率高。在本报告中，一名AML青少年患者在allo-HSCT治疗期间因HHV-6B脑炎导致视力障碍后成功治愈。移植后HHV-6脑炎相关视力障碍罕见，临床诊断和治疗具有挑战性，未来需要更多关注。
Zotero 插件