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经皮肾镜取石术后迟发性出血的 MiGUTS 列线图的外部验证。

External validation of the MiGUTS nomogram for the prediction of bleeding control intervention after renal trauma.

机构信息

Department of Urology, Kantonsspital Graubünden, Loëstrasse 170, Chur, CH-7000, Switzerland.

Department of Urology, University of Utah Health, Salt Lake City, USA.

出版信息

World J Urol. 2024 Sep 30;42(1):554. doi: 10.1007/s00345-024-05231-7.

Abstract

INTRODUCTION

The American Association for the Surgery of Trauma (AAST) renal trauma grading leads to a variable management of patients with high-grade renal injuries. For a better prediction of the risk for bleeding interventions, Keihani et al. introduced the multi-institutional genito-urinary trauma study (MiGUTS) renal trauma nomogram in 2019. The aim of this study was to conduct an external validation and generalization for all kidney trauma cases of the nomogram with a European cohort of a Swiss level 1 trauma center.

METHODS

We collected data from the clinical information system of the Kantonsspital Graubünden, Chur, Switzerland. All patients ≥ 18 years of age from 01.01.2008 to 01.12.2020 with a renal trauma who underwent computed tomography imaging of the abdomen were included. The descriptive analysis was performed by a t-test/Wilcoxon signed-rank test and a Chi-square test. The predictions of the nomogram were analysed by the Pearson correlation coefficient. The threshold of prediction of a bleeding intervention was optimized by a ROC analysis.

RESULTS

Overall, 166 patients were included. Most patients were male (80.7%) with a median age of 44 years. Using the prediction from the MiGUTS nomogram developed by Keihani et al. we were able to identify a threshold with a sensitivity of 1.00, specificity of 0.87, positive predictive value of 0.44, negative predictive value of 1.00 and accuracy of 0.88.

CONCLUSION

The MiGUTS nomogram by Keihani et al. demonstrated to be reliable in the prediction of an intervention for bleeding control in our validation study in a European cohort.

摘要

简介

美国创伤外科学会(AAST)的肾脏创伤分级导致了高分级肾损伤患者的治疗管理存在差异。为了更好地预测出血干预的风险,Keihani 等人于 2019 年引入了多机构泌尿生殖系统创伤研究(MiGUTS)肾脏创伤列线图。本研究的目的是使用瑞士一级创伤中心的欧洲队列对该列线图的所有肾脏创伤病例进行外部验证和推广。

方法

我们从瑞士库尔的 Graubünden 州立医院的临床信息系统中收集数据。纳入 2008 年 1 月 1 日至 2020 年 12 月 1 日期间年龄≥18 岁、接受腹部 CT 成像检查的肾创伤患者。采用 t 检验/Wilcoxon 符号秩检验和卡方检验进行描述性分析。通过 Pearson 相关系数分析列线图的预测。通过 ROC 分析优化出血干预预测的阈值。

结果

共有 166 例患者纳入研究。大多数患者为男性(80.7%),中位年龄为 44 岁。使用 Keihani 等人开发的 MiGUTS 列线图预测,我们能够确定一个阈值,其灵敏度为 1.00,特异性为 0.87,阳性预测值为 0.44,阴性预测值为 1.00,准确性为 0.88。

结论

在我们的欧洲队列验证研究中,Keihani 等人的 MiGUTS 列线图在预测出血控制干预方面表现可靠。

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