Wakabayashi Yasushi, Uesako Hayata, Kobayashi Masanori, Ichikawa Tomohide, Koyama Takashi, Abe Hidetoshi
Department of Cardiovascular Medicine, Matsumoto Kyoritsu Hospital, 9-26 Habaue, Matsumoto City, Nagano, 390-8505, Japan.
Heart Vessels. 2025 Apr;40(4):341-349. doi: 10.1007/s00380-024-02472-9. Epub 2024 Sep 30.
In patients with atrial fibrillation (AF) recurrence after pulmonary vein (PV) isolation, noninvasive markers predicting PV reconnection or PV reconnection sites have not been fully elucidated. This study investigated the relationship between the P-wave terminal force in lead V1 (PTFV1) and the PV reconnection or reconnection site in patients with AF recurrence. We retrospectively studied consecutive patients who underwent second AF ablation between April 1, 2018, and June 1, 2023. PTFV1 was investigated before the first AF ablation (pre-ablation PTFV1) and before the second AF ablation (post-ablation PTFV1). In addition, we examined the ratio of the post-ablation to pre-ablation PTFV1 (PTFV1 ratio). These values were compared between patients with and without PV reconnection, with and without left PV (LPV) reconnection, and with and without right PV (RPV) reconnection. The analysis included 56 patients. PTFV1 was reduced because of the first AF ablation. In addition, the values were more decreased in patients without PV reconnection than with PV reconnection. The PTFV1 ratio was significantly smaller in the patients without LPV reconnection than with LPV reconnection; no significant difference was observed between the patients with and without RPV reconnection. Receiver operating characteristic curve analysis showed that a PTFV1 ratio > 0.69 predicted LPV reconnection with 70.0% sensitivity and 66.7% specificity. In conclusion, the PTFV1 ratio may be a noninvasive marker predicting LPV reconnection in patients with AF recurrence.
在肺静脉(PV)隔离术后发生心房颤动(AF)复发的患者中,预测PV重新连接或PV重新连接部位的非侵入性标志物尚未完全阐明。本研究调查了V1导联P波终末电势(PTFV1)与AF复发患者PV重新连接或重新连接部位之间的关系。我们回顾性研究了2018年4月1日至2023年6月1日期间连续接受第二次AF消融的患者。在第一次AF消融前(消融前PTFV1)和第二次AF消融前(消融后PTFV1)对PTFV1进行了研究。此外,我们还检查了消融后与消融前PTFV1的比值(PTFV1比值)。比较了有或无PV重新连接、有或无左PV(LPV)重新连接以及有或无右PV(RPV)重新连接的患者之间的这些值。分析纳入了56例患者。由于第一次AF消融,PTFV1降低。此外,无PV重新连接的患者的值比有PV重新连接的患者下降得更多。无LPV重新连接的患者的PTFV1比值显著低于有LPV重新连接的患者;有或无RPV重新连接的患者之间未观察到显著差异。受试者工作特征曲线分析显示,PTFV1比值>0.69预测LPV重新连接的灵敏度为70.0%,特异度为66.7%。总之,PTFV1比值可能是预测AF复发患者LPV重新连接的非侵入性标志物。