Mak Daniel, Breidbart Emily, Mehta Shilpa, Kohn Brenda
Division of Pediatric Endocrinology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Division Pediatric Endocrinology and Diabetes, Department of Pediatrics, NYU Grossman School of Medicine, New York, New York, USA.
Horm Res Paediatr. 2024 Sep 30:1-4. doi: 10.1159/000541661.
This survey investigates brain MRI practices for isolated GHD among Pediatric Endocrine Society (PES) members, focusing on gadolinium-based contrast agents (GBCAs) versus non-contrast MRI.
A 15-question survey was distributed to 1,553 PES members, capturing data on GBCA usage, non-contrast imaging access, and awareness of gadolinium retention.
A total of 85% of respondents routinely order brain MRIs for isolated GHD, with 60% using GBCAs. Most respondents have access to high-resolution non-contrast imaging, though 54% are unaware of gadolinium retention risks.
High-resolution non-contrast MRI demonstrates diagnostic efficacy, suggesting a shift away from GBCAs in clinic practice for isolated GHD. The survey forms the basis to update PES guidelines in the evaluation of isolated GHD.
本调查研究了美国儿科学会内分泌学会（PES）成员针对孤立性生长激素缺乏症（GHD）进行脑部磁共振成像（MRI）检查的情况，重点关注基于钆的造影剂（GBCA）与非增强MRI的使用情况。
向1553名PES成员发放了一份包含15个问题的调查问卷，收集有关GBCA使用情况、非增强成像设备可及性以及钆潴留知晓情况的数据。
共有85%的受访者常规为孤立性GHD患者开具脑部MRI检查单，其中60%使用GBCA。大多数受访者能够进行高分辨率非增强成像检查，不过54%的人并不知晓钆潴留风险。
高分辨率非增强MRI显示出诊断效力，这表明在临床实践中针对孤立性GHD应减少GBCA的使用。该调查为更新PES关于孤立性GHD评估的指南奠定了基础。
