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老年人高血压的药物治疗。

Pharmacologic Treatment of Hypertension in Older Adults.

机构信息

Academic Unit for Ageing and Stroke Research, University of Leeds, Leeds, LS2 3AA, United Kingdom; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford BD9 6RJ, United Kingdom.

Academic Unit for Ageing and Stroke Research, University of Leeds, Leeds, LS2 3AA, United Kingdom.

出版信息

Clin Geriatr Med. 2024 Nov;40(4):629-644. doi: 10.1016/j.cger.2024.04.004. Epub 2024 May 28.

DOI:10.1016/j.cger.2024.04.004
PMID:39349036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11479625/
Abstract

The authors conducted a review of pharmacologic therapy in older adults with hypertension. They reviewed the evidence supporting their use in older adults, understanding the physiologic changes and potential adverse drug effects associated with aging and antihypertensive medication use, exploring guideline recommendations for antihypertensive use in older adults, and evaluating the associated risks and benefits of specific classes of antihypertensive medications.

摘要

作者对老年高血压患者的药物治疗进行了综述。他们回顾了支持在老年人群中使用这些药物的证据，了解与衰老和使用抗高血压药物相关的生理变化和潜在的药物不良反应，探讨了老年人群抗高血压药物使用的指南建议，并评估了特定类别的抗高血压药物的相关风险和获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/bcdc8750393e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/3d6dfa92088a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/3be5a8cf0119/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/bcdc8750393e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/3d6dfa92088a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/3be5a8cf0119/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2225/11479625/bcdc8750393e/gr3.jpg

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本文引用的文献

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Hypertension. 2024 Mar;81(3):e16-e30. doi: 10.1161/HYP.0000000000000236. Epub 2024 Jan 11.
2
Novel Prediction Equations for Absolute Risk Assessment of Total Cardiovascular Disease Incorporating Cardiovascular-Kidney-Metabolic Health: A Scientific Statement From the American Heart Association.纳入心血管-肾脏-代谢健康因素的全心血管疾病绝对风险评估新预测方程：美国心脏协会科学声明
Circulation. 2023 Dec 12;148(24):1982-2004. doi: 10.1161/CIR.0000000000001191. Epub 2023 Nov 10.
3
Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality.
全球可改变风险因素对心血管疾病和死亡的影响。
N Engl J Med. 2023 Oct 5;389(14):1273-1285. doi: 10.1056/NEJMoa2206916. Epub 2023 Aug 26.
4
The Effect of Frailty on the Efficacy and Safety of Intensive Blood Pressure Control: A Post Hoc Analysis of the SPRINT Trial.衰弱对强化血压控制疗效和安全性的影响：SPRINT 试验的事后分析。
Circulation. 2023 Aug 15;148(7):565-574. doi: 10.1161/CIRCULATIONAHA.123.064003. Epub 2023 Jul 4.
5
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA).2023ESH 动脉高血压管理指南 欧洲高血压学会动脉高血压管理工作组：得到国际高血压学会 (ISH) 和欧洲肾脏协会 (ERA) 的认可。
J Hypertens. 2023 Dec 1;41(12):1874-2071. doi: 10.1097/HJH.0000000000003480. Epub 2023 Sep 26.
6
Predicting the risk of acute kidney injury in primary care: derivation and validation of STRATIFY-AKI.预测初级保健中急性肾损伤的风险：STRATIFY-AKI 的推导和验证。
Br J Gen Pract. 2023 Jul 27;73(733):e605-e614. doi: 10.3399/BJGP.2022.0389. Print 2023 Aug.
7
The association between antihypertensive treatment and serious adverse events by age and frailty: A cohort study.抗高血压治疗与年龄和虚弱相关的严重不良事件的关联：一项队列研究。
PLoS Med. 2023 Apr 19;20(4):e1004223. doi: 10.1371/journal.pmed.1004223. eCollection 2023 Apr.
8
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PLoS Med. 2021 Nov 9;18(11):e1003821. doi: 10.1371/journal.pmed.1003821. eCollection 2021 Nov.